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Volume 5 Supplement 1

Proceedings of Fibroproliferative disorders: from biochemical analysis to targeted therapies

Proceedings

Edited by Petro E Petrides and David Brenner

Fibroproliferative disorders: from biochemical analysis to targeted therapies. Go to conference site.

Frauenchiemsee, Germany25-30 September 2010

  2. Lung development is a complex and finely balanced process. Yet the lung has a relatively limited repertoire of responses to injury, which, depending on severity of the injury and developmental stage and suscep...

    Authors: David Warburton
    Citation: Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S2
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  3. Novel approaches are needed to define subgroups of patients with Idiopathic pulmonary fibrosis (IPF) at risk for acute exacerbations and/or accelerated progression of this generally fatal disease. Progression ...

    Authors: Cory M Hogaboam, Glenda Trujillo and Fernando J Martinez
    Citation: Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S3
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  5. Myofibroblasts differentiate, invade and repair injured tissues by secreting and organizing the extracellular matrix and by developing contractile forces. When tissues are damaged, tissue homeostasis must be r...

    Authors: Ludovic Micallef, Nicolas Vedrenne, Fabrice Billet, Bernard Coulomb, Ian A Darby and Alexis Desmoulière
    Citation: Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S5
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  6. Fibrocytes, a group of bone marrow-derived mesenchymal progenitor cells, were first described in 1994 as fibroblast-like, peripheral blood cells that migrate to regions of tissue injury. These cells are unique...

    Authors: Adriana Blakaj and Richard Bucala
    Citation: Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S6
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  7. Several recent studies have demonstrated that endothelial to mesenchymal transition (EndoMT), a newly recognized type of cellular transdifferentiation may be an important source of myofibroblasts during the de...

    Authors: Sonsoles Piera-Velazquez and Sergio A Jimenez
    Citation: Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S7
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  8. Key roles for connective tissue growth factor (CTGF/CCN2) are demonstrated in the wound repair process where it promotes myofibroblast differentiation and angiogenesis. Similar mechanisms are active in tumor-r...

    Authors: Annica Jacobson and Janet L Cunningham
    Citation: Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S8
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  9. Lung fibrosis is the final common pathway of a large variety of chronic lung disorders, named interstitial lung diseases. The most aggressive form is the idiopathic pulmonary fibrosis [IPF] characterized by al...

    Authors: Annie Pardo and Moisés Selman
    Citation: Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S9
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  10. This review provides an introduction to mass spectrometry based proteomics and discusses several proteomics approaches that are relevant in understanding the pathophysiology of fibrotic disorders and the appro...

    Authors: Marjan Gucek
    Citation: Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S10
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  11. The wound-healing process induced by chronic hepatitis C virus (HCV) infection triggers liver damage characterized by fibrosis development and finally cirrhosis. Liver Transplantation (LT) is the optimal surgi...

    Authors: Ricardo Gehrau, Valeria Mas, Kellie Archer and Daniel Maluf
    Citation: Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S11
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  12. Activated hepatic stellate cells (HSC) play a central role in scar formation that leads to liver fibrosis. The molecular mechanisms underlying this process are not fully understood. Microarray and bioinformati...

    Authors: Hideaki Shimada and Lakshman E Rajagopalan
    Citation: Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S12
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  13. Chronic toxicities of locoregional and systemic oncological treatments commonly develop in long-term cancer survivors. Amongst these toxicities, post-radiotherapeutic complications alter patient's quality of l...

    Authors: Saad Hamama, Sylvie Delanian, Virginie Monceau and Marie-Catherine Vozenin
    Citation: Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S13
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  14. Fibrotic disorders are commonplace, take many forms and can be life-threatening. No better example of this exists than the progressive fibrosis that accompanies all chronic renal disease. Renal fibrosis is a d...

    Authors: Tim D Hewitson
    Citation: Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S14
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  15. The vasculature of the kidney is a heterogeneous structure, whose functional integrity is essential for the regulation of renal function. Owing to the importance of the endothelium in vascular biology, chronic...

    Authors: Dominique Guerrot, Jean-Claude Dussaule, Panagiotis Kavvadas, Jean-Jacques Boffa, Christos E Chadjichristos and Christos Chatziantoniou
    Citation: Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S15
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  17. Most chronic liver diseases of all etiologies result in progressive liver fibrosis. Myofibroblasts produce the extracellular matrix, including type I collagen, which constitutes the fibrous scar in liver fibro...

    Authors: David A Brenner, Tatiana Kisseleva, David Scholten, Yong Han Paik, Keiko Iwaisako, Sayaka Inokuchi, Bernd Schnabl, Ekihiro Seki, Samuele De Minicis, Christoph Oesterreicher and Kojiro Taura
    Citation: Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S17
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  18. Fibrosis in systemic sclerosis (SSc), a complex polygenic disease associated with autoimmunity and proliferative/obliterative vasculopathy, shares pathobiologic features in common with other fibrosing illnesse...

    Authors: Swati Bhattacharyya, Jun Wei, Warren G Tourtellotte, Monique Hinchcliff, Cara G Gottardi and John Varga
    Citation: Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S18
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  19. Despite significant advances have been made in the recent years regarding organ-specific therapies, there is no approved 'disease-modifying' antifibrotic drug for systemic sclerosis (SSc) available to date. Al...

    Authors: Naoki Iwamoto and Oliver Distler
    Citation: Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S19
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  20. Primary Myelofibrosis (PMF) is a chronic myeloproliferative neoplasm characterized by a clonal myeloproliferation and a myelofibrosis. The concomitant presence of neoangiogenesis and osteosclerosis suggests a ...

    Authors: Marie-Caroline Le Bousse-Kerdilès
    Citation: Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S20
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  21. A subset of myeloproliferative disorders (MPN) and myelodyplastic syndromes (MDS) evolves to fibrosis of the bone marrow associated with haematopoietic insufficiency. We have been interested in chemokines invo...

    Authors: Hans Kreipe, Guntram Büsche, Oliver Bock and Kais Hussein
    Citation: Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S21
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  24. CTGF is a secreted matricellular protein with very complex biology. It has been shown to modulate many signaling pathways leading to cell adhesion and migration, angiogenesis, myofibroblast activation, and ext...

    Authors: Kenneth E Lipson, Carol Wong, Yuchin Teng and Suzanne Spong
    Citation: Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S24
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  25. Bone marrow fibrosis is a hallmark of primary and post ET/PV myelofibrosis. To investigated the impact of replacement of the hematopoietic system in myelofibrosis patients by allogeneic stem cell transplantati...

    Authors: Nicolaus Kröger, Michael Kvasnicka and Jürgen Thiele
    Citation: Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S25
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  26. Liver fibrosis, and its end stage cirrhosis are a major cause of morbidity and mortality and therapeutic options are limited. However, the traditional view of liver disease as an irreversible process is obsole...

    Authors: Antonella Pellicoro, Prakash Ramachandran and John P Iredale
    Citation: Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S26
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  28. The dynamic process of epithelial-to-mesenchymal transition (EMT) is a causal event in kidney fibrosis. This cellular phenotypic transition involves activation of transcriptional responses and remodeling of ce...

    Authors: Shreyasi Das, Bryan N Becker, F Michael Hoffmann and Janet E Mertz
    Citation: Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S28
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  29. The overall aim of presented study is to test the inhibition of the formation of collagen fibrils as the novel approach to reduce accumulation of pathological fibrotic deposits. The main hypothesis is that by ...

    Authors: Andrzej Steplewski and Andrzej Fertala
    Citation: Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S29
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Fibrogenesis & Tissue Repair

ISSN: 1755-1536

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