Friedman SL: Evolving challenges in hepatic fibrosis. Nat Rev Gastroenterol Hepatol. 2010, 7: 425-436. 10.1038/nrgastro.2010.97.
Article
PubMed
Google Scholar
Friedman SL: Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. J Biol Chem. 2000, 275: 2247-2250. 10.1074/jbc.275.4.2247.
Article
CAS
PubMed
Google Scholar
Kawada N: Evolution of hepatic fibrosis research. Hepatol Res. 2011, 41: 199-208. 10.1111/j.1872-034X.2011.00776.x.
Article
CAS
PubMed
Google Scholar
Bataller R, Brenner DA: Hepatic stellate cells as a target for the treatment of liver fibrosis. Semin Liv Dis. 2001, 21: 437-451. 10.1055/s-2001-17558.
Article
CAS
Google Scholar
Bartel DP: MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004, 116: 281-297. 10.1016/S0092-8674(04)00045-5.
Article
CAS
PubMed
Google Scholar
Ambros V: The functions of animal microRNAs. Nature. 2004, 16: 350-355.
Article
Google Scholar
Ji R, Cheng Y, Yue J, Yang J, Liu X, Chen H, Dean DB, Zhang C: MicroRNA expression signature and antisense-mediated depletion reveal an essential role of microRNA in vascular neointimal lesion formation. Circ Res. 2007, 100: 1579-1588. 10.1161/CIRCRESAHA.106.141986.
Article
CAS
PubMed
Google Scholar
Ikeda S, Kong SW, Lu J, Bisping E, Zhang H, Allen PD, Golub TR, Pieske B, Pu WT: Altered microRNA expression in human heart disease. Physiol Genomics. 2007, 31: 367-373. 10.1152/physiolgenomics.00144.2007.
Article
CAS
PubMed
Google Scholar
Carè A, Catalucci D, Felicetti F, Bonci D, Addario A, Gallo P, Bang ML, Segnalini P, Gu Y, Dalton ND, Elia L, Latronico MV, Høydal M, Autore C, Russo MA, Dorn GW, Ellingsen O, Ruiz-Lozano P, Peterson KL, Croce CM, Peschle C, Condorelli G: MicroRNA-133 controls cardiac hypertrophy. Nat Med. 2007, 13: 613-618. 10.1038/nm1582.
Article
PubMed
Google Scholar
Pandey P, Brors B, Srivastava PK, Bott A, Boehn SN, Groene HJ, Gretz N: Microarray-based approach identifies microRNAs and their target functional patterns in polycystic kidney disease. BMC Genomics. 2008, 9: 624-10.1186/1471-2164-9-624.
Article
PubMed Central
PubMed
Google Scholar
Dillhoff M, Wojcik SE, Bloomston M: MicroRNAs in solid tumors. J Surg Res. 2009, 154: 349-354. 10.1016/j.jss.2008.02.046.
Article
PubMed Central
CAS
PubMed
Google Scholar
Huang Q, Gumireddy K, Schrier M, le Sage C, Nagel R, Nair S, Egan DA, Li A, Huang G, Klein-Szanto AJ, Gimotty PA, Katsaros D, Coukos G, Zhang L, Puré E, Agami R: The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis. Nat Cell Biol. 2008, 10: 202-210. 10.1038/ncb1681.
Article
CAS
PubMed
Google Scholar
Mitchell PS, Parkin RK, Kroh EM, Fritz BR, Wyman SK, Pogosova-Agadjanyan EL, Peterson A, Noteboom J, O’Briant KC, Allen A, Lin DW, Urban N, Drescher CW, Knudsen BS, Stirewalt DL, Gentleman R, Vessella RL, Nelson PS, Martin DB, Tewari M: Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci U S A. 2008, 105: 10513-10518. 10.1073/pnas.0804549105.
Article
PubMed Central
CAS
PubMed
Google Scholar
Chen X, Ba Y, Ma L, Cai X, Yin Y, Wang K, Guo J, Zhang Y, Chen J, Guo X, Li Q, Li X, Wang W, Zhang Y, Wang J, Jiang X, Xiang Y, Xu C, Zheng P, Zhang J, Li R, Zhang H, Shang X, Gong T, Ning G, Wang J, Zen K, Zhang J, Zhang CY: Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res. 2008, 18: 997-1006. 10.1038/cr.2008.282.
Article
CAS
PubMed
Google Scholar
Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, Sweet-Cordero A, Ebert BL, Mak RH, Ferrando AA, Downing JR, Jacks T, Horvitz HR, Golub TR: MicroRNA expression profiles classify human cancers. Nature. 2005, 435: 834-838. 10.1038/nature03702.
Article
CAS
PubMed
Google Scholar
Jopling CL, Yi M, Lancaster AM, Lemon SM, Sarnow P: Modulation of hepatitis C virus RNA abundance by a liver-specific microRNA. Science. 2005, 309: 1577-1581. 10.1126/science.1113329.
Article
CAS
PubMed
Google Scholar
Li YP, Gottwein JM, Scheel TK, Jensen TB, Bukh J: MicroRNA-122 antagonism against hepatitis C virus genotypes 1–6 and reduced efficacy by host RNA insertion or mutations in the HCV 5′ UTR. Proc Natl Acad Sci U S A. 2011, 108: 4991-4996. 10.1073/pnas.1016606108.
Article
PubMed Central
CAS
PubMed
Google Scholar
Yamaura Y, Nakajima M, Takagi S, Fukami T, Tsuneyama K, Yokoi T: Plasma microRNA profiles in rat models of hepatocellular injury, cholestasis, and steatosis. PLoS One. 2012, 7: e30250-10.1371/journal.pone.0030250.
Article
PubMed Central
CAS
PubMed
Google Scholar
Ogawa T, Iizuka M, Sekiya Y, Yoshizato K, Ikeda K, Kawada N: Suppression of type I collagen production by microRNA-29b in cultured human stellate cells. Biochem Biophys Res Commun. 2010, 391: 316-321. 10.1016/j.bbrc.2009.11.056.
Article
CAS
PubMed
Google Scholar
Sekiya Y, Ogawa T, Yoshizato K, Ikeda K, Kawada N: Suppression of hepatic stellate cell activation by microRNA-29b. Biochem Biophys Res Commun. 2011, 412: 74-79. 10.1016/j.bbrc.2011.07.041.
Article
CAS
PubMed
Google Scholar
Lakner AM, Steuerwald NM, Walling TL, Ghosh S, Li T, McKillop IH, Russo MW, Bonkovsky HL, Schrum LW: Inhibitory effects of microRNA 19b in hepatic stellate cell-mediated fibrogenesis. Hepatology. 2012, 56: 300-310.
Article
PubMed Central
CAS
PubMed
Google Scholar
Lee YB, Bantounas I, Lee DY, Phylactou L, Caldwell MA, Uney JB: Twist-1 regulates the miR-199a/214 cluster during development. Nucleic Acids Res. 2009, 37: 123-128. 10.1093/nar/gkn920.
Article
PubMed Central
CAS
PubMed
Google Scholar
Denby L, Ramdas V, McBride MW, Wang J, Robinson H, McClure J, Crawford W, Lu R, Hillyard DZ, Khanin R, Agami R, Dominiczak AF, Sharpe CC, Baker AH: miR-21 and miR-214 are consistently modulated during renal injury in rodent models. Am J Pathol. 2011, 179: 661-672. 10.1016/j.ajpath.2011.04.021.
Article
PubMed Central
CAS
PubMed
Google Scholar
van Mil A, Grundmann S, Goumans MJ, Lei Z, Oerlemans MI, Jaksani S, Doevendans PA, Sluijter JP: MicroRNA-214 inhibits angiogenesis by targeting Quaking and reducing angiogenic growth factor release. Cardiovasc Res. 2012, 93: 655-665. 10.1093/cvr/cvs003.
Article
CAS
PubMed
Google Scholar
Ogawa T, Enomoto M, Fujii H, Sekiya Y, Yoshizato K, Ikeda K, Kawada N: MicroRNA-221/222 upregulation indicates the activation of stellate cells and the progression of liver fibrosis. Gut. 2012, Epub ahead of print
Google Scholar
Mu YP, Ogawa T, Kawada N: Reversibility of fibrosis, inflammation, and endoplasmic reticulum stress in the liver of rats fed a methionine-choline-deficient diet. Lab Invest. 2010, 90: 245-56. 10.1038/labinvest.2009.123.
Article
CAS
PubMed
Google Scholar
Derfoul A, Juan AH, Difilippantonio MJ, Palanisamy N, Ried T, Sartorelli V: Decreased microRNA-214 levels in breast cancer cells coincides with increased cell proliferation, invasion and accumulation of the Polycomb Ezh2 methyltransferase. Carcinogenesis. 2011, 32: 1607-1614. 10.1093/carcin/bgr184.
Article
PubMed Central
CAS
PubMed
Google Scholar
Vaksman O, Stavnes HT, Kaern J, Trope CG, Davidson B, Reich R: miRNA profiling along tumour progression in ovarian carcinoma. J Cell Mol Med. 2011, 15: 1593-1602. 10.1111/j.1582-4934.2010.01148.x.
Article
PubMed Central
CAS
PubMed
Google Scholar
Penna E, Orso F, Cimino D, Tenaglia E, Lembo A, Quaglino E, Poliseno L, Haimovic A, Osella-Abate S, De Pittà C, Pinatel E, Stadler MB, Provero P, Bernengo MG, Osman I, Taverna D: microRNA-214 contributes to melanoma tumour progression through suppression of TFAP2C. EMBO J. 2011, 30: 1990-2007. 10.1038/emboj.2011.102.
Article
PubMed Central
CAS
PubMed
Google Scholar
Qiang R, Wang F, Shi LY, Liu M, Chen S, Wan HY, Li YX, Li X, Gao SY, Sun BC, Tang H: Plexin-B1 is a target of miR-214 in cervical cancer and promotes the growth and invasion of HeLa cells. Int J Biochem Cell Biol. 2011, 43: 632-641. 10.1016/j.biocel.2011.01.002.
Article
CAS
PubMed
Google Scholar
Murakami Y, Toyoda H, Tanaka M, Kuroda M, Harada Y, Matsuda F, Tajima A, Kosaka N, Ochiya T, Shimotohno K: The progression of liver fibrosis is related with overexpression of the miR-199 and 200 families. PLoS One. 2011, 6: e16081-10.1371/journal.pone.0016081.
Article
PubMed Central
CAS
PubMed
Google Scholar
Roderburg C, Urban GW, Bettermann K, Vucur M, Zimmermann H, Schmidt S, Janssen J, Koppe C, Knolle P, Castoldi M, Tacke F, Trautwein C, Luedde T: Micro-RNA profiling reveals a role for miR-29 in human and murine liver fibrosis. Hepatology. 2011, 53: 209-218. 10.1002/hep.23922.
Article
CAS
PubMed
Google Scholar
Venugopal SK, Jiang J, Kim TH, Li Y, Wang SS, Torok NJ, Wu J, Zern MA: Liver fibrosis causes downregulation of miRNA-150 and miRNA-194 in hepatic stellate cells, and their overexpression causes decreased stellate cell activation. Am J Physiol Gastrointest Liver Physiol. 2010, 298: G101-106. 10.1152/ajpgi.00220.2009.
Article
PubMed Central
CAS
PubMed
Google Scholar
Yang Z, Chen S, Luan X, Li Y, Liu M, Li X, Liu T, Tang H: MicroRNA-214 is aberrantly expressed in cervical cancers and inhibits the growth of HeLa cells. IUBMB Life. 2009, 61: 1075-1082. 10.1002/iub.252.
Article
CAS
PubMed
Google Scholar
Yang H, Kong W, He L, Zhao JJ, O’Donnell JD, Wang J, Wenham RM, Coppola D, Kruk PA, Nicosia SV, Cheng JQ: MicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTEN. Cancer Res. 2008, 68: 425-433. 10.1158/0008-5472.CAN-07-2488.
Article
CAS
PubMed
Google Scholar
Juan AH, Kumar RM, Marx JG, Young RA, Sartorelli V: Mir-214-dependent regulation of the polycomb protein Ezh2 in skeletal muscle and embryonic stem cells. Mol Cell. 2009, 36: 61-74. 10.1016/j.molcel.2009.08.008.
Article
PubMed Central
CAS
PubMed
Google Scholar
Bedossa P, Poynard T: An algorithm for the grading of activity in chronic hepatitis C. The METAVIR Cooperative Study Group. Hepatology. 1996, 24: 289-293.
CAS
Google Scholar
Xu L, Hui AY, Albanis E, Arthur MJ, O’Byrne SM, Blaner WS, Mukherjee P, Friedman SL, Eng FJ: Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis. Gut. 2005, 54: 142-151. 10.1136/gut.2004.042127.
Article
PubMed Central
CAS
PubMed
Google Scholar
Kristensen DB, Kawada N, Imamura K, Miyamoto Y, Tateno C, Seki S, Kuroki T, Yoshizato K: Proteome analysis of rat hepatic stellate cells. Hepatology. 2000, 32: 268-277. 10.1053/jhep.2000.9322.
Article
CAS
PubMed
Google Scholar