Figure 1
From: Induction of microRNA-214-5p in human and rodent liver fibrosis
miR-214-5p expression in the livers of patients with chronic hepatitis C virus infection. miR-214-5p expression in the livers of 35 hepatitis C virus (HCV)-infected patients was analyzed using real-time PCR. (A) Representative sirius red staining of liver tissues with fibrosis stages F1-F4 of chronic hepatitis C patients included in this study. (B) miR-214-5p expression in samples from each stage of liver fibrosis (METAVIR scoring system). The numbers of patients in each stage were: F1, 17; F2, 8; F3, 8; and F4, 2. The Jonckheere-Terpstra test identified trends among classes. (C) Comparison of miR-214-5p expression in F1/F2 and F3/F4 samples. (D) Comparison of miR-214-5p expression between F1 and F2-4. The levels of miR-214-5p expression in B, C and D are indicated relative to F1, F1/F2 and F1, respectively. *P < 0.05.