Hannivoort RA, Hernandez-gea V, Friedman SL: Genomics and proteomics in liver fibrosis and cirrhosis. Fibrogenesis & Tissue Repair. 2012, 5: 1-10.1186/1755-1536-5-1.
Article
CAS
Google Scholar
Hoshida Y, Villanueva A, Kobayashi M, Peix J, Chiang DY, Camargo A, Gupta S, Moore J, Wrobel MJ, Lerner J, Reich M, Chan JA, Glickman JN, Ikeda K, Hashimoto M, Watanabe G, Daidone MG, Roayaie S, Schwartz M, Thung S, Salvesen HB, Gabriel S, Mazzaferro V, Bruix J, Friedman SL, Kumada H, Llovet JM, Golub TR: Gene expression in fixed tissues and outcome in hepatocellular carcinoma. N Engl J Med. 2008, 359: 1995-2004. 10.1056/NEJMoa0804525.
Article
PubMed Central
CAS
PubMed
Google Scholar
Flagella M, Bui S, Zheng Z, Nguyen CT, Zhang A, Pastor L, Ma Y, Yang W, Crawford KL, McMaster GK, Witney F, Luo Y: A multiplex branched DNA assay for parallel quantitative gene expression profiling. Anal Biochem. 2006, 352: 50-60. 10.1016/j.ab.2006.02.013.
Article
CAS
PubMed
Google Scholar
Cheng K, Mahato RI: Gene modulation for treating liver fibrosis. Crit Rev Ther Drug Carrier Syst. 2007, 24: 93-146. 10.1615/CritRevTherDrugCarrierSyst.v24.i2.10.
Article
PubMed Central
CAS
PubMed
Google Scholar
Shimada H, Staten NR, Rajagopalan LE: TGF-β1 mediated activation of Rho kinase induces TGF-β2 and endothelin-1 expression in human hepatic stellate cells. J Hepatol. 2011, 54: 521-528. 10.1016/j.jhep.2010.07.026.
Article
CAS
PubMed
Google Scholar
Xu L, Hui AY, Albanis E, Arthur MJ, O’Byrne SM, Blaner WS, Mukherjee P, Friedman SL, Eng FJ: Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis. Gut. 2005, 54: 142-151. 10.1136/gut.2004.042127.
Article
PubMed Central
CAS
PubMed
Google Scholar
Agresti A: Categorical Data Analysis. 2002, Wiley, Hoboken, NJ, USA, 2
Book
Google Scholar
SAS Institute, Inc: The GENMOD Procedure. 1999, SAS Institute, Inc, Cary, NC
Google Scholar
Boers W, Aarrass S, Linthorst C, Pinzani M, Elferink RO, Bosma P: Transcriptional profiling reveals novel markers of liver fibrogenesis: gremlin and insulin-like growth factor binding proteins. J Biol Chem. 2006, 281: 16289-16295. 10.1074/jbc.M600711200.
Article
CAS
PubMed
Google Scholar
De Minicis S, Seki E, Uchinami H, Klume J, Zhang Y, Brenner DA, Schwabe RF: Gene expression profiles during hepatic stellate cell activation in culture and in vivo. Gastroenterology. 2007, 132: 1937-1946. 10.1053/j.gastro.2007.02.033.
Article
CAS
PubMed
Google Scholar
Missiha SB, Ostrowski M, Heathcote EJ: Disease progression in chronic hepatitis C: modifiable and non-modifiable factors. Gastroenterology. 2008, 134: 1699-1714. 10.1053/j.gastro.2008.02.069.
Article
CAS
PubMed
Google Scholar
Trépo E, Potthoff A, Pradat P, Bakshi R, Young B, Lagier R, Moreno C, Verset L, Cross R, Degré D, Lemmers A, Gustot T, Berthillon P, Rosenberg W, Trépo C, Sninsky J, Adler M, Wedemeyer H: Role of cirrhosis risk score for the early prediction of fibrosis progression in hepatitis C patients with minimal liver disease. J Hepatol. 2011, 55: 38-44. 10.1016/j.jhep.2010.10.018.
Article
PubMed
Google Scholar
Asselah T, Bieche I, Laurendeau I, Paradis V, Vidaud D, Degott C, Martinot M, Bedossa P, Valla D, Vidaud M, Marcellin P: Liver gene expression signature of mild fibrosis in patients with chronic hepatitis C. Gastroenterology. 2005, 129: 2064-2075. 10.1053/j.gastro.2005.09.010.
Article
CAS
PubMed
Google Scholar
Chen CZC, Raghunath M: Focus on collagen: in vitro systems to study fibrogenesis and antifibrosis – state of the art. Fibrogenesis & Tissue Repair. 2009, 2: 7-10.1186/1755-1536-2-7.
Article
Google Scholar
Seth D, Hogg PJ, Gorrell MD, McCaughan GW, Haber PS: Direct effects of alcohol on hepatic fibrinolytic balance: implications for alcoholic liver disease. J Hepatol. 2008, 48: 614-627. 10.1016/j.jhep.2007.12.015.
Article
CAS
PubMed
Google Scholar
Kido O, Fukushima K, Ueno Y, Inoue J, Jefferson DM, Shimosegawa T: Compensatory role of inducible annexin A2 for impaired biliary epithelial anion-exchange activity of imflammatory cholangiopathy. Lab Invest. 2009, 89: 1374-1386. 10.1038/labinvest.2009.105.
Article
CAS
PubMed
Google Scholar
Gressner OA, Lahme B, Gressner AM: Gc-globulin (vitamin D binding protein) is synthesized and secreted by hepatocytes and internalized by hepatic stellate cells through Ca2+−dependent interaction with the megalin/gp330 receptor. Clin Chim Acta. 2008, 390: 28-37. 10.1016/j.cca.2007.12.011.
Article
CAS
PubMed
Google Scholar
Yang W, Maqsodi B, Ma Y, Bui S, Crawford KL, McMaster GK, Witney F, Luo Y: Direct quantification of gene expression in homogenates of formalin-fixed, paraffin-embedded tissues. Biotechniques. 2006, 40: 481-486. 10.2144/000112133.
Article
CAS
PubMed
Google Scholar
Knodell RG, Ishak KG, Black WC, Chen TS, Craig R, Kaplowitz N, Kiernan TW, Wollman J: Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. Hepatology. 1981, 1: 431-435. 10.1002/hep.1840010511.
Article
CAS
PubMed
Google Scholar
Poynard T, Bedossa P, Opolon P: Natural history of liver fibrosis progression in patients withchronic hepatitis C. The OBSVIRC, METAVIR, CLINIVIR, and DOSVIRC groups. Lancet. 1997, 349: 825-832. 10.1016/S0140-6736(96)07642-8.
Article
CAS
PubMed
Google Scholar
Knudsen BS, Allen AN, McLerran DF, Vessella RL, Karademos J, Davies JE, Maqsodi B, McMaster GK, Kristal AR: Evaluation of the branched-chain DNA assay for measurement of RNA in formalin-fixed tissues. J Mol Diagn. 2008, 10: 169-176. 10.2353/jmoldx.2008.070127.
Article
PubMed Central
CAS
PubMed
Google Scholar
Bushnell S, Budde J, Catino T, Cole J, Derti A, Kelso R, Collins ML, Molino G, Sheridan P, Monahan J, Urdea M: ProbeDesigner: for the design of probesets for branched DNA (bDNA) signal amplification assays. Bioinformatics. 1999, 15: 348-355. 10.1093/bioinformatics/15.5.348.
Article
CAS
PubMed
Google Scholar
Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A, Speleman F: Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol. 2002, 3: RESEARCH0034.
Article
PubMed Central
PubMed
Google Scholar
Benjamini Y, Hochberg Y: Controlling the false discovery rate: a practical and powerful approach to multiple testing. J Royal Stat Soc. 1995, 57: 289-300.
Google Scholar