Coresh J, Astor BC, Greene T, Eknoyan G, Levey AS: Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey. Am J Kidney Dis. 2003, 41: 1-12. 10.1053/ajkd.2003.50007.
Article
PubMed
Google Scholar
Matsuo S, Imai E, Horio M, Yasuda Y, Tomita K, Nitta K, Yamagata K, Tomino Y, Yokoyama H, Hishida A: Revised equations for estimated GFR from serum creatinine in Japan. Am J Kidney Dis. 2009, 53: 982-992. 10.1053/j.ajkd.2008.12.034.
Article
CAS
PubMed
Google Scholar
Folkman J: Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med. 1995, 1: 27-31. 10.1038/nm0195-27.
Article
CAS
PubMed
Google Scholar
Kitamoto Y, Tokunaga H, Tomita K: Vascular endothelial growth factor is an essential molecule for mouse kidney development: glomerulogenesis and nephrogenesis. J Clin Invest. 1997, 99: 2351-2357. 10.1172/JCI119416.
Article
PubMed Central
CAS
PubMed
Google Scholar
Tufro A, Norwood VF, Carey RM, Gomez RA: Vascular endothelial growth factor induces nephrogenesis and vasculogenesis. J Am Soc Nephrol. 1999, 10: 2125-2134.
CAS
PubMed
Google Scholar
Woolf AS, Yuan HT: Angiopoietin growth factors and Tie receptor tyrosine kinases in renal vascular development. Pediatr Nephrol. 2001, 16: 177-184. 10.1007/s004670000509.
Article
CAS
PubMed
Google Scholar
Hara A, Wada T, Furuichi K, Sakai N, Kawachi H, Shimizu F, Shibuya M, Matsushima K, Yokoyama H, Egashira K, Kaneko S: Blockade of VEGF accelerates proteinuria, via decrease in nephrin expression in rat crescentic glomerulonephritis. Kidney Int. 2006, 69: 1986-1995. 10.1038/sj.ki.5000439.
Article
CAS
PubMed
Google Scholar
Kang DH, Joly AH, Oh SW, Hugo C, Kerjaschki D, Gordon KL, Mazzali M, Jefferson JA, Hughes J, Madsen KM, Schreiner GF, Johnson RJ: Impaired angiogenesis in the remnant kidney model: I. Potential role of vascular endothelial growth factor and thrombospondin-1. J Am Soc Nephrol. 2001, 12: 1434-1447.
CAS
PubMed
Google Scholar
Kang DH, Anderson S, Kim YG, Mazzalli M, Suga S, Jefferson JA, Gordon KL, Oyama TT, Hughes J, Hugo C, Kerjaschki D, Schreiner GF, Johnson RJ: Impaired angiogenesis in the aging kidney: vascular endothelial growth factor and thrombospondin-1 in renal disease. Am J Kidney Dis. 2001, 37: 601-611. 10.1016/S0272-6386(01)80019-6.
Article
CAS
PubMed
Google Scholar
Cooper ME, Vranes D, Youssef S, Stacker SA, Cox AJ, Rizkalla B, Casley DJ, Bach LA, Kelly DJ, Gilbert RE: Increased renal expression of vascular endothelial growth factor (VEGF) and its receptor VEGFR-2 in experimental diabetes. Diabetes. 1999, 48: 2229-2239. 10.2337/diabetes.48.11.2229.
Article
CAS
PubMed
Google Scholar
Long DA, Woolf AS, Suda T, Yuan HT: Increased renal angiopoietin-1 expression in folic acid-induced nephrotoxicity in mice. J Am Soc Nephrol. 2001, 12: 2721-2731.
CAS
PubMed
Google Scholar
Yuan HT, Tipping PG, Li XZ, Long DA, Woolf AS: Angiopoietin correlates with glomerular capillary loss in anti-glomerular basement membrane glomerulonephritis. Kidney Int. 2002, 61: 2078-2089. 10.1046/j.1523-1755.2002.00381.x.
Article
CAS
PubMed
Google Scholar
Rizkalla B, Forbes JM, Cao Z, Boner G, Cooper ME: Temporal renal expression of angiogenic growth factors and their receptors in experimental diabetes: role of the renin-angiotensin system. J Hypertens. 2005, 23: 153-164. 10.1097/00004872-200501000-00026.
Article
CAS
PubMed
Google Scholar
Masuda Y, Shimizu A, Mori T, Ishiwata T, Kitamura H, Ohashi R, Ishizaki M, Asano G, Sugisaki Y, Yamanaka N: Vascular endothelial growth factor enhances glomerular capillary repair and accelerates resolution of experimentally induced glomerulonephritis. Am J Pathol. 2001, 159: 599-608. 10.1016/S0002-9440(10)61731-2.
Article
PubMed Central
CAS
PubMed
Google Scholar
Shimizu A, Masuda Y, Mori T, Kitamura H, Ishizaki M, Sugisaki Y, Fukuda Y: Vascular endothelial growth factor165 resolves glomerular inflammation and accelerates glomerular capillary repair in rat anti-glomerular basement membrane glomerulonephritis. J Am Soc Nephrol. 2004, 15: 2655-2665. 10.1097/01.ASN.0000141038.28733.F2.
Article
CAS
PubMed
Google Scholar
Ostendorf T, Kunter U, Eitner F, Loos A, Regele H, Kerjaschki D, Henninger DD, Janjic N, Floege J: VEGF(165) mediates glomerular endothelial repair. J Clin Invest. 1999, 104: 913-923. 10.1172/JCI6740.
Article
PubMed Central
CAS
PubMed
Google Scholar
Kang DH, Hughes J, Mazzali M, Schreiner GF, Johnson RJ: Impaired angiogenesis in the remnant kidney model: II. Vascular endothelial growth factor administration reduces renal fibrosis and stabilizes renal function. J Am Soc Nephrol. 2001, 12: 1448-1457.
CAS
PubMed
Google Scholar
Kim YG, Suga SI, Kang DH, Jefferson JA, Mazzali M, Gordon KL, Matsui K, Breiteneder-Geleff S, Shankland SJ, Hughes J, Kerjaschki D, Schreiner GF, Johnson RJ: Vascular endothelial growth factor accelerates renal recovery in experimental thrombotic microangiopathy. Kidney Int. 2000, 58: 2390-2399. 10.1046/j.1523-1755.2000.00422.x.
Article
CAS
PubMed
Google Scholar
de Vriese AS, Tilton RG, Elger M, Stephan CC, Kriz W, Lameire NH: Antibodies against vascular endothelial growth factor improve early renal dysfunction in experimental diabetes. J Am Soc Nephrol. 2001, 12: 993-1000.
CAS
PubMed
Google Scholar
Flyvbjerg A, Dagnaes-Hansen F, De Vriese AS, Schrijvers BF, Tilton RG, Rasch R: Amelioration of long-term renal changes in obese type 2 diabetic mice by a neutralizing vascular endothelial growth factor antibody. Diabetes. 2002, 51: 3090-3094. 10.2337/diabetes.51.10.3090.
Article
CAS
PubMed
Google Scholar
Sung SH, Ziyadeh FN, Wang A, Pyagay PE, Kanwar YS, Chen S: Blockade of vascular endothelial growth factor signaling ameliorates diabetic albuminuria in mice. J Am Soc Nephrol. 2006, 17: 3093-3104. 10.1681/ASN.2006010064.
Article
CAS
PubMed
Google Scholar
Kim W, Moon SO, Lee SY, Jang KY, Cho CH, Koh GY, Choi KS, Yoon KH, Sung MJ, Kim DH, Lee S, Kang KP, Park SK: COMP-angiopoietin-1 ameliorates renal fibrosis in a unilateral ureteral obstruction model. J Am Soc Nephrol. 2006, 17: 2474-2483. 10.1681/ASN.2006020109.
Article
CAS
PubMed
Google Scholar
Eremina V, Sood M, Haigh J, Nagy A, Lajoie G, Ferrara N, Gerber HP, Kikkawa Y, Miner JH, Quaggin SE: Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases. J Clin Invest. 2003, 111: 707-716.
Article
PubMed Central
CAS
PubMed
Google Scholar
Nyengaard JR, Rasch R: The impact of experimental diabetes mellitus in rats on glomerular capillary number and sizes. Diabetologia. 1993, 36: 189-194. 10.1007/BF00399948.
Article
CAS
PubMed
Google Scholar
Yamamoto Y, Maeshima Y, Kitayama H, Kitamura S, Takazawa Y, Sugiyama H, Yamasaki Y, Makino H: Tumstatin Peptide, an inhibitor of angiogenesis, prevents glomerular hypertrophy in the early stage of diabetic nephropathy. Diabetes. 2004, 53: 1831-1840. 10.2337/diabetes.53.7.1831.
Article
CAS
PubMed
Google Scholar
Ichinose K, Maeshima Y, Yamamoto Y, Kitayama H, Takazawa Y, Hirokoshi K, Sugiyama H, Yamasaki Y, Eguchi K, Makino H: Anti-angiogenic endostatin peptide ameliorates renal alterations in the early stage of type 1 diabetic nephropathy model. Diabetes. 2005, 54: in press-10.2337/diabetes.54.10.2891.
Article
Google Scholar
Ichinose K, Maeshima Y, Yamamoto Y, Kinomura M, Hirokoshi K, Kitayama H, Takazawa Y, Sugiyama H, Yamasaki Y, Agata N, Makino H: 2-(8-hydroxy-6-methoxy-1-oxo-1h-2-benzopyran-3-yl) propionic acid, an inhibitor of angiogenesis, ameliorates renal alterations in obese type 2 diabetic mice. Diabetes. 2006, 55: 1232-1242. 10.2337/db05-1367.
Article
CAS
PubMed
Google Scholar
Zhang SX, Wang JJ, Lu K, Mott R, Longeras R, Ma JX: Therapeutic potential of angiostatin in diabetic nephropathy. J Am Soc Nephrol. 2006, 17: 475-486. 10.1681/ASN.2005020217.
Article
CAS
PubMed
Google Scholar
Wang JJ, Zhang SX, Mott R, Knapp RR, Cao W, Lau K, Ma JX: Salutary effect of pigment epithelium-derived factor in diabetic nephropathy: evidence for antifibrogenic activities. Diabetes. 2006, 55: 1678-1685. 10.2337/db05-1448.
Article
CAS
PubMed
Google Scholar
Nasu T, Maeshima Y, Kinomura M, Hirokoshi-Kawahara K, Tanabe K, Sugiyama H, Sonoda H, Sato Y, Makino H: Vasohibin-1, a negative feedback regulator of angiogenesis, ameliorates renal alterations in a mouse model of diabetic nephropathy. Diabetes. 2009, 58: 2365-2375. 10.2337/db08-1790.
Article
PubMed Central
CAS
PubMed
Google Scholar
Ferrara N, Davis-Smyth T: The biology of vascular endothelial growth factor. Endocr Rev. 1997, 18: 4-25. 10.1210/er.18.1.4.
Article
CAS
PubMed
Google Scholar
Karkkainen MJ, Makinen T, Alitalo K: Lymphatic endothelium: a new frontier of metastasis research. Nat Cell Biol. 2002, 4: E2-5. 10.1038/ncb0102-e2.
Article
CAS
PubMed
Google Scholar
Ferrara N, Carver-Moore K, Chen H, Dowd M, Lu L, O'Shea KS, Powell-Braxton L, Hillan KJ, Moore MW: Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature. 1996, 380: 439-442. 10.1038/380439a0.
Article
CAS
PubMed
Google Scholar
Carmeliet P, Ferreira V, Breier G, Pollefeyt S, Kieckens L, Gertsenstein M, Fahrig M, Vandenhoeck A, Harpal K, Eberhardt C, Declercq C, Pawling J, Moons L, Collen D, Risau W, Nagy A: Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature. 1996, 380: 435-439. 10.1038/380435a0.
Article
CAS
PubMed
Google Scholar
Leung DW, Cachianes G, Kuang WJ, Goeddel DV, Ferrara N: Vascular endothelial growth factor is a secreted angiogenic mitogen. Science. 1989, 246: 1306-1309. 10.1126/science.2479986.
Article
CAS
PubMed
Google Scholar
Gerber HP, McMurtrey A, Kowalski J, Yan M, Keyt BA, Dixit V, Ferrara N: Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation. J Biol Chem. 1998, 273: 30336-30343. 10.1074/jbc.273.46.30336.
Article
CAS
PubMed
Google Scholar
Bates DO, Curry FE: Vascular endothelial growth factor increases microvascular permeability via a Ca(2+)-dependent pathway. Am J Physiol. 1997, 273: H687-694.
CAS
PubMed
Google Scholar
Barleon B, Sozzani S, Zhou D, Weich HA, Mantovani A, Marme D: Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1. Blood. 1996, 87: 3336-3343.
CAS
PubMed
Google Scholar
Tilton RG, Chang KC, LeJeune WS, Stephan CC, Brock TA, Williamson JR: Role for nitric oxide in the hyperpermeability and hemodynamic changes induced by intravenous VEGF. Invest Ophthalmol Vis Sci. 1999, 40: 689-696.
CAS
PubMed
Google Scholar
Satchell SC, Braet F: Glomerular endothelial cell fenestrations: an integral component of the glomerular filtration barrier. Am J Physiol Renal Physiol. 2009, 296: F947-956. 10.1152/ajprenal.90601.2008.
Article
PubMed Central
CAS
PubMed
Google Scholar
Houck KA, Ferrara N, Winer J, Cachianes G, Li B, Leung DW: The vascular endothelial growth factor family: identification of a fourth molecular species and characterization of alternative splicing of RNA. Mol Endocrinol. 1991, 5: 1806-1814. 10.1210/mend-5-12-1806.
Article
CAS
PubMed
Google Scholar
Tischer E, Mitchell R, Hartman T, Silva M, Gospodarowicz D, Fiddes JC, Abraham JA: The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing. J Biol Chem. 1991, 266: 11947-11954.
CAS
PubMed
Google Scholar
Bates DO, Cui TG, Doughty JM, Winkler M, Sugiono M, Shields JD, Peat D, Gillatt D, Harper SJ: VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, is down-regulated in renal cell carcinoma. Cancer Res. 2002, 62: 4123-4131.
CAS
PubMed
Google Scholar
Park JE, Keller GA, Ferrara N: The vascular endothelial growth factor (VEGF) isoforms: differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF. Mol Biol Cell. 1993, 4: 1317-1326.
Article
PubMed Central
CAS
PubMed
Google Scholar
Semenza G: Signal transduction to hypoxia-inducible factor 1. Biochem Pharmacol. 2002, 64: 993-998. 10.1016/S0006-2952(02)01168-1.
Article
CAS
PubMed
Google Scholar
Soker S, Takashima S, Miao HQ, Neufeld G, Klagsbrun M: Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell. 1998, 92: 735-745. 10.1016/S0092-8674(00)81402-6.
Article
CAS
PubMed
Google Scholar
Brown LF, Berse B, Tognazzi K, Manseau EJ, Van de Water L, Senger DR, Dvorak HF, Rosen S: Vascular permeability factor mRNA and protein expression in human kidney. Kidney Int. 1992, 42: 1457-1461. 10.1038/ki.1992.441.
Article
CAS
PubMed
Google Scholar
Kretzler M, Schroppel B, Merkle M, Huber S, Mundel P, Horster M, Schlondorff D: Detection of multiple vascular endothelial growth factor splice isoforms in single glomerular podocytes. Kidney Int Suppl. 1998, 67: S159-161. 10.1046/j.1523-1755.1998.06733.x.
Article
CAS
PubMed
Google Scholar
Iijima K, Yoshikawa N, Connolly DT, Nakamura H: Human mesangial cells and peripheral blood mononuclear cells produce vascular permeability factor. Kidney Int. 1993, 44: 959-966. 10.1038/ki.1993.337.
Article
CAS
PubMed
Google Scholar
Liu E, Morimoto M, Kitajima S, Koike T, Yu Y, Shiiki H, Nagata M, Watanabe T, Fan J: Increased expression of vascular endothelial growth factor in kidney leads to progressive impairment of glomerular functions. J Am Soc Nephrol. 2007, 18: 2094-2104. 10.1681/ASN.2006010075.
Article
CAS
PubMed
Google Scholar
Hakroush S, Moeller MJ, Theilig F, Kaissling B, Sijmonsma TP, Jugold M, Akeson AL, Traykova-Brauch M, Hosser H, Hahnel B, Grone HJ, Koesters R, Kriz W: Effects of increased renal tubular vascular endothelial growth factor (VEGF) on fibrosis, cyst formation, and glomerular disease. Am J Pathol. 2009, 175: 1883-1895. 10.2353/ajpath.2009.080792.
Article
PubMed Central
CAS
PubMed
Google Scholar
Veron D, Reidy KJ, Bertuccio C, Teichman J, Villegas G, Jimenez J, Shen W, Kopp JB, Thomas DB, Tufro A: Overexpression of VEGF-A in podocytes of adult mice causes glomerular disease. Kidney Int. 77: 989-999. 10.1038/ki.2010.64.
Eremina V, Jefferson JA, Kowalewska J, Hochster H, Haas M, Weisstuch J, Richardson C, Kopp JB, Kabir MG, Backx PH, Gerber HP, Ferrara N, Barisoni L, Alpers CE, Quaggin SE: VEGF inhibition and renal thrombotic microangiopathy. N Engl J Med. 2008, 358: 1129-1136. 10.1056/NEJMoa0707330.
Article
PubMed Central
CAS
PubMed
Google Scholar
Sugimoto H, Hamano Y, Charytan D, Cosgrove D, Kieran M, Sudhakar A, Kalluri R: Neutralization of circulating vascular endothelial growth factor (VEGF) by anti-VEGF antibodies and soluble VEGF receptor 1 (sFlt-1) induces proteinuria. J Biol Chem. 2003, 278: 12605-12608. 10.1074/jbc.C300012200.
Article
CAS
PubMed
Google Scholar
Cui TG, Foster RR, Saleem M, Mathieson PW, Gillatt DA, Bates DO, Harper SJ: Differentiated human podocytes endogenously express an inhibitory isoform of vascular endothelial growth factor (VEGF165b) mRNA and protein. Am J Physiol Renal Physiol. 2004, 286: F767-773. 10.1152/ajprenal.00337.2003.
Article
CAS
PubMed
Google Scholar
Drash A, Sherman F, Hartmann WH, Blizzard RM: A syndrome of pseudohermaphroditism, Wilms' tumor, hypertension, and degenerative renal disease. J Pediatr. 1970, 76: 585-593. 10.1016/S0022-3476(70)80409-7.
Article
CAS
PubMed
Google Scholar
Schumacher VA, Jeruschke S, Eitner F, Becker JU, Pitschke G, Ince Y, Miner JH, Leuschner I, Engers R, Everding AS, Bulla M, Royer-Pokora B: Impaired glomerular maturation and lack of VEGF165b in Denys-Drash syndrome. J Am Soc Nephrol. 2007, 18: 719-729. 10.1681/ASN.2006020124.
Article
CAS
PubMed
Google Scholar
de Vries C, Escobedo JA, Ueno H, Houck K, Ferrara N, Williams LT: The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science. 1992, 255: 989-991. 10.1126/science.1312256.
Article
CAS
PubMed
Google Scholar
Kendall RL, Thomas KA: Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor. Proc Natl Acad Sci USA. 1993, 90: 10705-10709. 10.1073/pnas.90.22.10705.
Article
PubMed Central
CAS
PubMed
Google Scholar
Fong GH, Zhang L, Bryce DM, Peng J: Increased hemangioblast commitment, not vascular disorganization, is the primary defect in flt-1 knock-out mice. Development. 1999, 126: 3015-3025.
CAS
PubMed
Google Scholar
Simon M, Grone HJ, Johren O, Kullmer J, Plate KH, Risau W, Fuchs E: Expression of vascular endothelial growth factor and its receptors in human renal ontogenesis and in adult kidney. Am J Physiol. 1995, 268: F240-250.
CAS
PubMed
Google Scholar
Simon M, Rockl W, Hornig C, Grone EF, Theis H, Weich HA, Fuchs E, Yayon A, Grone HJ: Receptors of vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) in fetal and adult human kidney: localization and [125I]VEGF binding sites. J Am Soc Nephrol. 1998, 9: 1032-1044.
CAS
PubMed
Google Scholar
Chen S, Kasama Y, Lee JS, Jim B, Marin M, Ziyadeh FN: Podocyte-derived vascular endothelial growth factor mediates the stimulation of alpha3(IV) collagen production by transforming growth factor-beta1 in mouse podocytes. Diabetes. 2004, 53: 2939-2949. 10.2337/diabetes.53.11.2939.
Article
CAS
PubMed
Google Scholar
Ku CH, White KE, Dei Cas A, Hayward A, Webster Z, Bilous R, Marshall S, Viberti G, Gnudi L: Inducible overexpression of sFlt-1 in podocytes ameliorates glomerulopathy in diabetic mice. Diabetes. 2008, 57: 2824-2833. 10.2337/db08-0647.
Article
PubMed Central
CAS
PubMed
Google Scholar
Ferrara N, Gerber HP, LeCouter J: The biology of VEGF and its receptors. Nat Med. 2003, 9: 669-676. 10.1038/nm0603-669.
Article
CAS
PubMed
Google Scholar
Shalaby F, Rossant J, Yamaguchi TP, Gertsenstein M, Wu XF, Breitman ML, Schuh AC: Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature. 1995, 376: 62-66. 10.1038/376062a0.
Article
CAS
PubMed
Google Scholar
Guo D, Jia Q, Song HY, Warren RS, Donner DB: Vascular endothelial cell growth factor promotes tyrosine phosphorylation of mediators of signal transduction that contain SH2 domains. Association with endothelial cell proliferation. J Biol Chem. 1995, 270: 6729-6733. 10.1074/jbc.270.12.6729.
Article
CAS
PubMed
Google Scholar
Eliceiri BP, Paul R, Schwartzberg PL, Hood JD, Leng J, Cheresh DA: Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability. Mol Cell. 1999, 4: 915-924. 10.1016/S1097-2765(00)80221-X.
Article
CAS
PubMed
Google Scholar
Takahashi T, Ueno H, Shibuya M: VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells. Oncogene. 1999, 18: 2221-2230. 10.1038/sj.onc.1202527.
Article
CAS
PubMed
Google Scholar
Thomas S, Vanuystel J, Gruden G, Rodriguez V, Burt D, Gnudi L, Hartley B, Viberti G: Vascular endothelial growth factor receptors in human mesangium in vitro and in glomerular disease. J Am Soc Nephrol. 2000, 11: 1236-1243.
CAS
PubMed
Google Scholar
Katavetin P: VEGF inhibition and renal thrombotic microangiopathy. N Engl J Med. 2008, 359: 205-206. 10.1056/NEJMc080770. author reply 206-207
Article
CAS
PubMed
Google Scholar
Kawasaki T, Kitsukawa T, Bekku Y, Matsuda Y, Sanbo M, Yagi T, Fujisawa H: A requirement for neuropilin-1 in embryonic vessel formation. Development. 1999, 126: 4895-4902.
CAS
PubMed
Google Scholar
Harper SJ, Xing CY, Whittle C, Parry R, Gillatt D, Peat D, Mathieson PW: Expression of neuropilin-1 by human glomerular epithelial cells in vitro and in vivo. Clin Sci (Lond). 2001, 101: 439-446. 10.1042/CS20010025.
Article
CAS
Google Scholar
Karihaloo A, Karumanchi SA, Cantley WL, Venkatesha S, Cantley LG, Kale S: Vascular endothelial growth factor induces branching morphogenesis/tubulogenesis in renal epithelial cells in a neuropilin-dependent fashion. Mol Cell Biol. 2005, 25: 7441-7448. 10.1128/MCB.25.17.7441-7448.2005.
Article
PubMed Central
CAS
PubMed
Google Scholar
Yancopoulos GD, Davis S, Gale NW, Rudge JS, Wiegand SJ, Holash J: Vascular-specific growth factors and blood vessel formation. Nature. 2000, 407: 242-248. 10.1038/35025215.
Article
CAS
PubMed
Google Scholar
Thurston G, Rudge JS, Ioffe E, Zhou H, Ross L, Croll SD, Glazer N, Holash J, McDonald DM, Yancopoulos GD: Angiopoietin-1 protects the adult vasculature against plasma leakage. Nat Med. 2000, 6: 460-463. 10.1038/74725.
Article
CAS
PubMed
Google Scholar
Suri C, Jones PF, Patan S, Bartunkova S, Maisonpierre PC, Davis S, Sato TN, Yancopoulos GD: Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell. 1996, 87: 1171-1180. 10.1016/S0092-8674(00)81813-9.
Article
CAS
PubMed
Google Scholar
Maisonpierre PC, Suri C, Jones PF, Bartunkova S, Wiegand SJ, Radziejewski C, Compton D, McClain J, Aldrich TH, Papadopoulos N, Daly TJ, Davis S, Sato TN, Yancopoulos GD: Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science. 1997, 277: 55-60. 10.1126/science.277.5322.55.
Article
CAS
PubMed
Google Scholar
Yuan HT, Khankin EV, Karumanchi SA, Parikh SM: Angiopoietin 2 is a partial agonist/antagonist of Tie2 signaling in the endothelium. Mol Cell Biol. 2009, 29: 2011-2022. 10.1128/MCB.01472-08.
Article
PubMed Central
CAS
PubMed
Google Scholar
Yuan HT, Venkatesha S, Chan B, Deutsch U, Mammoto T, Sukhatme VP, Woolf AS, Karumanchi SA: Activation of the orphan endothelial receptor Tie1 modifies Tie2-mediated intracellular signaling and cell survival. FASEB J. 2007, 21: 3171-3183. 10.1096/fj.07-8487com.
Article
CAS
PubMed
Google Scholar
Gale NW, Thurston G, Hackett SF, Renard R, Wang Q, McClain J, Martin C, Witte C, Witte MH, Jackson D, Suri C, Campochiaro PA, Wiegand SJ, Yancopoulos GD: Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1. Dev Cell. 2002, 3: 411-423. 10.1016/S1534-5807(02)00217-4.
Article
CAS
PubMed
Google Scholar
Satchell SC, Harper SJ, Tooke JE, Kerjaschki D, Saleem MA, Mathieson PW: Human podocytes express angiopoietin 1, a potential regulator of glomerular vascular endothelial growth factor. J Am Soc Nephrol. 2002, 13: 544-550.
CAS
PubMed
Google Scholar
Woolf AS, Gnudi L, Long DA: Roles of angiopoietins in kidney development and disease. J Am Soc Nephrol. 2009, 20: 239-244. 10.1681/ASN.2008020243.
Article
CAS
PubMed
Google Scholar
Yuan HT, Suri C, Landon DN, Yancopoulos GD, Woolf AS: Angiopoietin-2 is a site-specific factor in differentiation of mouse renal vasculature. J Am Soc Nephrol. 2000, 11: 1055-1066.
CAS
PubMed
Google Scholar
Davis B, Dei Cas A, Long DA, White KE, Hayward A, Ku CH, Woolf AS, Bilous R, Viberti G, Gnudi L: Podocyte-specific expression of angiopoietin-2 causes proteinuria and apoptosis of glomerular endothelia. J Am Soc Nephrol. 2007, 18: 2320-2329. 10.1681/ASN.2006101093.
Article
CAS
PubMed
Google Scholar
Oh H, Takagi H, Suzuma K, Otani A, Matsumura M, Honda Y: Hypoxia and vascular endothelial growth factor selectively up-regulate angiopoietin-2 in bovine microvascular endothelial cells. J Biol Chem. 1999, 274: 15732-15739. 10.1074/jbc.274.22.15732.
Article
CAS
PubMed
Google Scholar
Pola R, Ling LE, Silver M, Corbley MJ, Kearney M, Blake Pepinsky R, Shapiro R, Taylor FR, Baker DP, Asahara T, Isner JM: The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors. Nat Med. 2001, 7: 706-711. 10.1038/89083.
Article
CAS
PubMed
Google Scholar
Holder N, Klein R: Eph receptors and ephrins: effectors of morphogenesis. Development. 1999, 126: 2033-2044.
CAS
PubMed
Google Scholar
Kullander K, Klein R: Mechanisms and functions of Eph and ephrin signalling. Nat Rev Mol Cell Biol. 2002, 3: 475-486. 10.1038/nrm856.
Article
CAS
PubMed
Google Scholar
Gerety SS, Wang HU, Chen ZF, Anderson DJ: Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development. Mol Cell. 1999, 4: 403-414. 10.1016/S1097-2765(00)80342-1.
Article
CAS
PubMed
Google Scholar
Wang HU, Chen ZF, Anderson DJ: Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4. Cell. 1998, 93: 741-753. 10.1016/S0092-8674(00)81436-1.
Article
CAS
PubMed
Google Scholar
Adams RH, Wilkinson GA, Weiss C, Diella F, Gale NW, Deutsch U, Risau W, Klein R: Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis. Genes Dev. 1999, 13: 295-306. 10.1101/gad.13.3.295.
Article
PubMed Central
CAS
PubMed
Google Scholar
Marme D: The impact of anti-angiogenic agents on cancer therapy. J Cancer Res Clin Oncol. 2003, 129: 607-620. 10.1007/s00432-003-0488-9.
Article
PubMed
Google Scholar
Takahashi T, Takahashi K, Gerety S, Wang H, Anderson DJ, Daniel TO: Temporally compartmentalized expression of ephrin-B2 during renal glomerular development. J Am Soc Nephrol. 2001, 12: 2673-2682.
CAS
PubMed
Google Scholar
Baldwin C, Chen ZW, Bedirian A, Yokota N, Nasr SH, Rabb H, Lemay S: Upregulation of EphA2 during in vivo and in vitro renal ischemia-reperfusion injury: role of Src kinases. Am J Physiol Renal Physiol. 2006, 291: F960-971. 10.1152/ajprenal.00020.2006.
Article
CAS
PubMed
Google Scholar
Ogawa K, Wada H, Okada N, Harada I, Nakajima T, Pasquale EB, Tsuyama S: EphB2 and ephrin-B1 expressed in the adult kidney regulate the cytoarchitecture of medullary tubule cells through Rho family GTPases. J Cell Sci. 2006, 119: 559-570. 10.1242/jcs.02777.
Article
CAS
PubMed
Google Scholar
Hashimoto T, Karasawa T, Saito A, Miyauchi N, Han GD, Hayasaka K, Shimizu F, Kawachi H: Ephrin-B1 localizes at the slit diaphragm of the glomerular podocyte. Kidney Int. 2007, 72: 954-964. 10.1038/sj.ki.5002454.
Article
CAS
PubMed
Google Scholar
Klahr S, Schreiner G, Ichikawa I: The progression of renal disease. N Engl J Med. 1988, 318: 1657-1666. 10.1056/NEJM198806233182505.
Article
CAS
PubMed
Google Scholar
Makino H, Kashihara N, Sugiyama H, Kanao K, Sekikawa T, Okamoto K, Maeshima Y, Ota Z, Nagai R: Phenotypic modulation of the mesangium reflected by contractile proteins in diabetes. Diabetes. 1996, 45: 488-495. 10.2337/diabetes.45.4.488.
Article
CAS
PubMed
Google Scholar
Maeshima Y, Kashihara N, Yasuda T, Sugiyama H, Sekikawa T, Okamoto K, Kanao K, Watanabe Y, Kanwar YS, Makino H: Inhibition of mesangial cell proliferation by E2F decoy oligodeoxynucleotide in vitro and in vivo. J Clin Invest. 1998, 101: 2589-2597. 10.1172/JCI429.
Article
PubMed Central
PubMed
Google Scholar
Kawachi H, Oite T, Shimizu F: Quantitative study of mesangial injury with proteinuria induced by monoclonal antibody 1-22-3. Clin Exp Immunol. 1993, 92: 342-346. 10.1111/j.1365-2249.1993.tb03402.x.
Article
PubMed Central
CAS
PubMed
Google Scholar
Shimizu A, Masuda Y, Kitamura H, Ishizaki M, Sugisaki Y, Yamanaka N: Recovery of damaged glomerular capillary network with endothelial cell apoptosis in experimental proliferative glomerulonephritis. Nephron. 1998, 79: 206-214. 10.1159/000045026.
Article
CAS
PubMed
Google Scholar
Kriz W, Hahnel B, Hosser H, Ostendorf T, Gaertner S, Kranzlin B, Gretz N, Shimizu F, Floege J: Pathways to recovery and loss of nephrons in anti-Thy-1 nephritis. J Am Soc Nephrol. 2003, 14: 1904-1926. 10.1097/01.ASN.0000070073.79690.57.
Article
PubMed
Google Scholar
Shulman K, Rosen S, Tognazzi K, Manseau EJ, Brown LF: Expression of vascular permeability factor (VPF/VEGF) is altered in many glomerular diseases. J Am Soc Nephrol. 1996, 7: 661-666.
CAS
PubMed
Google Scholar
Ohashi R, Shimizu A, Masuda Y, Kitamura H, Ishizaki M, Sugisaki Y, Yamanaka N: Peritubular capillary regression during the progression of experimental obstructive nephropathy. J Am Soc Nephrol. 2002, 13: 1795-1805. 10.1097/01.ASN.0000018408.51388.57.
Article
PubMed
Google Scholar
Sawano A, Iwai S, Sakurai Y, Ito M, Shitara K, Nakahata T, Shibuya M: Flt-1, vascular endothelial growth factor receptor 1, is a novel cell surface marker for the lineage of monocyte-macrophages in humans. Blood. 2001, 97: 785-791. 10.1182/blood.V97.3.785.
Article
CAS
PubMed
Google Scholar
Roberts JM, Cooper DW: Pathogenesis and genetics of pre-eclampsia. Lancet. 2001, 357: 53-56. 10.1016/S0140-6736(00)03577-7.
Article
CAS
PubMed
Google Scholar
Roberts JM, Taylor RN, Musci TJ, Rodgers GM, Hubel CA, McLaughlin MK: Preeclampsia: an endothelial cell disorder. Am J Obstet Gynecol. 1989, 161: 1200-1204.
Article
CAS
PubMed
Google Scholar
Rodgers GM, Taylor RN, Roberts JM: Preeclampsia is associated with a serum factor cytotoxic to human endothelial cells. Am J Obstet Gynecol. 1988, 159: 908-914.
Article
CAS
PubMed
Google Scholar
Kupferminc MJ, Daniel Y, Englender T, Baram A, Many A, Jaffa AJ, Gull I, Lessing JB: Vascular endothelial growth factor is increased in patients with preeclampsia. Am J Reprod Immunol. 1997, 38: 302-306. 10.1111/j.1600-0897.1997.tb00519.x.
Article
CAS
PubMed
Google Scholar
Livingston JC, Chin R, Haddad B, McKinney ET, Ahokas R, Sibai BM: Reductions of vascular endothelial growth factor and placental growth factor concentrations in severe preeclampsia. Am J Obstet Gynecol. 2000, 183: 1554-1557. 10.1067/mob.2000.108022.
Article
CAS
PubMed
Google Scholar
Levine RJ, Maynard SE, Qian C, Lim KH, England LJ, Yu KF, Schisterman EF, Thadhani R, Sachs BP, Epstein FH, Sibai BM, Sukhatme VP, Karumanchi SA: Circulating angiogenic factors and the risk of preeclampsia. N Engl J Med. 2004, 350: 672-683. 10.1056/NEJMoa031884.
Article
CAS
PubMed
Google Scholar
Vuorela P, Helske S, Hornig C, Alitalo K, Weich H, Halmesmaki E: Amniotic fluid--soluble vascular endothelial growth factor receptor-1 in preeclampsia. Obstet Gynecol. 2000, 95: 353-357. 10.1016/S0029-7844(99)00565-7.
Article
CAS
PubMed
Google Scholar
Zhou Y, McMaster M, Woo K, Janatpour M, Perry J, Karpanen T, Alitalo K, Damsky C, Fisher SJ: Vascular endothelial growth factor ligands and receptors that regulate human cytotrophoblast survival are dysregulated in severe preeclampsia and hemolysis, elevated liver enzymes, and low platelets syndrome. Am J Pathol. 2002, 160: 1405-1423. 10.1016/S0002-9440(10)62567-9.
Article
PubMed Central
CAS
PubMed
Google Scholar
Koga K, Osuga Y, Yoshino O, Hirota Y, Ruimeng X, Hirata T, Takeda S, Yano T, Tsutsumi O, Taketani Y: Elevated serum soluble vascular endothelial growth factor receptor 1 (sVEGFR-1) levels in women with preeclampsia. J Clin Endocrinol Metab. 2003, 88: 2348-2351. 10.1210/jc.2002-021942.
Article
CAS
PubMed
Google Scholar
Di Marco GS, Reuter S, Hillebrand U, Amler S, Konig M, Larger E, Oberleithner H, Brand E, Pavenstadt H, Brand M: The soluble VEGF receptor sFlt1 contributes to endothelial dysfunction in CKD. J Am Soc Nephrol. 2009, 20: 2235-2245. 10.1681/ASN.2009010061.
Article
CAS
PubMed
Google Scholar
Schramek H, Sarkozi R, Lauterberg C, Kronbichler A, Pirklbauer M, Albrecht R, Noppert SJ, Perco P, Rudnicki M, Strutz FM, Mayer G: Neuropilin-1 and neuropilin-2 are differentially expressed in human proteinuric nephropathies and cytokine-stimulated proximal tubular cells. Lab Invest. 2009, 89: 1304-1316. 10.1038/labinvest.2009.96.
Article
CAS
PubMed
Google Scholar
Ritz E, Rychlik I, Locatelli F, Halimi S: End-stage renal failure in type 2 diabetes: A medical catastrophe of worldwide dimensions. Am J Kidney Dis. 1999, 34: 795-808. 10.1016/S0272-6386(99)70035-1.
Article
CAS
PubMed
Google Scholar
Osterby R, Parving HH, Nyberg G, Hommel E, Jorgensen HE, Lokkegaard H, Svalander C: A strong correlation between glomerular filtration rate and filtration surface in diabetic nephropathy. Diabetologia. 1988, 31: 265-270.
CAS
PubMed
Google Scholar
Makino H, Yamasaki Y, Haramoto T, Shikata K, Hironaka K, Ota Z, Kanwar YS: Ultrastructural changes of extracellular matrices in diabetic nephropathy revealed by high resolution scanning and immunoelectron microscopy. Lab Invest. 1993, 68: 45-55.
CAS
PubMed
Google Scholar
Sharma K, Ziyadeh FN: Hyperglycemia and diabetic kidney disease. The case for transforming growth factor-beta as a key mediator. Diabetes. 1995, 44: 1139-1146. 10.2337/diabetes.44.10.1139.
Article
CAS
PubMed
Google Scholar
Flyvbjerg A: Putative pathophysiological role of growth factors and cytokines in experimental diabetic kidney disease. Diabetologia. 2000, 43: 1205-1223. 10.1007/s001250051515.
Article
CAS
PubMed
Google Scholar
Osterby R, Nyberg G: New vessel formation in the renal corpuscles in advanced diabetic glomerulopathy. J Diabet Complications. 1987, 1: 122-127. 10.1016/S0891-6632(87)80069-7.
Article
CAS
PubMed
Google Scholar
Kanesaki Y, Suzuki D, Uehara G, Toyoda M, Katoh T, Sakai H, Watanabe T: Vascular endothelial growth factor gene expression is correlated with glomerular neovascularization in human diabetic nephropathy. Am J Kidney Dis. 2005, 45: 288-294. 10.1053/j.ajkd.2004.09.020.
Article
CAS
PubMed
Google Scholar
Hohenstein B, Hausknecht B, Boehmer K, Riess R, Brekken RA, Hugo CP: Local VEGF activity but not VEGF expression is tightly regulated during diabetic nephropathy in man. Kidney Int. 2006, 69: 1654-1661. 10.1038/sj.ki.5000294.
Article
CAS
PubMed
Google Scholar
Osterby R, Bangstad HJ, Nyberg G, Rudberg S: On glomerular structural alterations in type-1 diabetes. Companions of early diabetic glomerulopathy. Virchows Arch. 2001, 438: 129-135. 10.1007/s004280000311.
Article
CAS
PubMed
Google Scholar
Guo M, Ricardo SD, Deane JA, Shi M, Cullen-McEwen L, Bertram JF: A stereological study of the renal glomerular vasculature in the db/db mouse model of diabetic nephropathy. J Anat. 2005, 207: 813-821. 10.1111/j.1469-7580.2005.00492.x.
Article
PubMed Central
PubMed
Google Scholar
Tsuchida K, Makita Z, Yamagishi S, Atsumi T, Miyoshi H, Obara S, Ishida M, Ishikawa S, Yasumura K, Koike T: Suppression of transforming growth factor beta and vascular endothelial growth factor in diabetic nephropathy in rats by a novel advanced glycation end product inhibitor, OPB-9195. Diabetologia. 1999, 42: 579-588. 10.1007/s001250051198.
Article
CAS
PubMed
Google Scholar
Hovind P, Tarnow L, Oestergaard PB, Parving HH: Elevated vascular endothelial growth factor in type 1 diabetic patients with diabetic nephropathy. Kidney Int Suppl. 2000, 75: S56-61. 10.1046/j.1523-1755.2000.07504.x.
Article
CAS
PubMed
Google Scholar
Kim NH, Oh JH, Seo JA, Lee KW, Kim SG, Choi KM, Baik SH, Choi DS, Kang YS, Han SY, Han KH, Ji YH, Cha DR: Vascular endothelial growth factor (VEGF) and soluble VEGF receptor FLT-1 in diabetic nephropathy. Kidney Int. 2005, 67: 167-177. 10.1111/j.1523-1755.2005.00067.x.
Article
CAS
PubMed
Google Scholar
Cha DR, Kim NH, Yoon JW, Jo SK, Cho WY, Kim HK, Won NH: Role of vascular endothelial growth factor in diabetic nephropathy. Kidney Int Suppl. 2000, 77: S104-112. 10.1046/j.1523-1755.2000.07717.x.
Article
CAS
PubMed
Google Scholar
Baelde HJ, Eikmans M, Doran PP, Lappin DW, de Heer E, Bruijn JA: Gene expression profiling in glomeruli from human kidneys with diabetic nephropathy. Am J Kidney Dis. 2004, 43: 636-650. 10.1053/j.ajkd.2003.12.028.
Article
CAS
PubMed
Google Scholar
Lindenmeyer MT, Kretzler M, Boucherot A, Berra S, Yasuda Y, Henger A, Eichinger F, Gaiser S, Schmid H, Rastaldi MP, Schrier RW, Schlondorff D, Cohen CD: Interstitial vascular rarefaction and reduced VEGF-A expression in human diabetic nephropathy. J Am Soc Nephrol. 2007, 18: 1765-1776. 10.1681/ASN.2006121304.
Article
CAS
PubMed
Google Scholar
Wolf G, Chen S, Ziyadeh FN: From the periphery of the glomerular capillary wall toward the center of disease: podocyte injury comes of age in diabetic nephropathy. Diabetes. 2005, 54: 1626-1634. 10.2337/diabetes.54.6.1626.
Article
CAS
PubMed
Google Scholar
Foster RR, Hole R, Anderson K, Satchell SC, Coward RJ, Mathieson PW, Gillatt DA, Saleem MA, Bates DO, Harper SJ: Functional evidence that vascular endothelial growth factor may act as an autocrine factor on human podocytes. Am J Physiol Renal Physiol. 2003, 284: F1263-1273.
Article
CAS
PubMed
Google Scholar
Nakagawa T: Uncoupling of the VEGF-endothelial nitric oxide axis in diabetic nephropathy: an explanation for the paradoxical effects of VEGF in renal disease. Am J Physiol Renal Physiol. 2007, 292: F1665-1672. 10.1152/ajprenal.00495.2006.
Article
CAS
PubMed
Google Scholar
Nakagawa T, Sato W, Glushakova O, Heinig M, Clarke T, Campbell-Thompson M, Yuzawa Y, Atkinson MA, Johnson RJ, Croker B: Diabetic endothelial nitric oxide synthase knockout mice develop advanced diabetic nephropathy. J Am Soc Nephrol. 2007, 18: 539-550. 10.1681/ASN.2006050459.
Article
CAS
PubMed
Google Scholar
Sato W, Kosugi T, Zhang L, Roncal CA, Heinig M, Campbell-Thompson M, Yuzawa Y, Atkinson MA, Grant MB, Croker BP, Nakagawa T: The pivotal role of VEGF on glomerular macrophage infiltration in advanced diabetic nephropathy. Lab Invest. 2008, 88: 949-961. 10.1038/labinvest.2008.60.
Article
CAS
PubMed
Google Scholar
Futrakul N, Butthep P, Futrakul P: Altered vascular homeostasis in chronic kidney disease. Clin Hemorheol Microcirc. 2008, 38: 201-207.
CAS
PubMed
Google Scholar
Long DA, Price KL, Ioffe E, Gannon CM, Gnudi L, White KE, Yancopoulos GD, Rudge JS, Woolf AS: Angiopoietin-1 therapy enhances fibrosis and inflammation following folic acid-induced acute renal injury. Kidney Int. 2008, 74: 300-309. 10.1038/ki.2008.179.
Article
CAS
PubMed
Google Scholar
Lemieux C, Maliba R, Favier J, Theoret JF, Merhi Y, Sirois MG: Angiopoietins can directly activate endothelial cells and neutrophils to promote proinflammatory responses. Blood. 2005, 105: 1523-1530. 10.1182/blood-2004-09-3531.
Article
CAS
PubMed
Google Scholar
Aplin AC, Gelati M, Fogel E, Carnevale E, Nicosia RF: Angiopoietin-1 and vascular endothelial growth factor induce expression of inflammatory cytokines before angiogenesis. Physiol Genomics. 2006, 27: 20-28. 10.1152/physiolgenomics.00048.2006.
Article
CAS
PubMed
Google Scholar
Rizkalla B, Forbes JM, Cooper ME, Cao Z: Increased renal vascular endothelial growth factor and angiopoietins by angiotensin II infusion is mediated by both AT1 and AT2 receptors. J Am Soc Nephrol. 2003, 14: 3061-3071. 10.1097/01.ASN.0000099374.58607.C9.
Article
CAS
PubMed
Google Scholar
Kitayama H, Maeshima Y, Takazawa Y, Yamamoto Y, Wu Y, Ichinose K, Hirokoshi K, Sugiyama H, Yamasaki Y, Makino H: Regulation of angiogenic factors in angiotensin II infusion model in association with tubulointerstitial injuries. Am J Hypertens. 2006, 19: 718-727. 10.1016/j.amjhyper.2005.09.022.
Article
CAS
PubMed
Google Scholar
Fiedler U, Reiss Y, Scharpfenecker M, Grunow V, Koidl S, Thurston G, Gale NW, Witzenrath M, Rosseau S, Suttorp N, Sobke A, Herrmann M, Preissner KT, Vajkoczy P, Augustin HG: Angiopoietin-2 sensitizes endothelial cells to TNF-alpha and has a crucial role in the induction of inflammation. Nat Med. 2006, 12: 235-239. 10.1038/nm1351.
Article
CAS
PubMed
Google Scholar
Peters H, Border WA, Noble NA: Angiotensin II blockade and low-protein diet produce additive therapeutic effects in experimental glomerulonephritis. Kidney Int. 2000, 57: 1493-1501. 10.1046/j.1523-1755.2000.00994.x.
Article
CAS
PubMed
Google Scholar
Wenzel UO, Thaiss F, Helmchen U, Stahl RA, Wolf G: Angiotensin II infusion ameliorates the early phase of a mesangioproliferative glomerulonephritis. Kidney Int. 2002, 61: 1020-1029. 10.1046/j.1523-1755.2002.00192.x.
Article
CAS
PubMed
Google Scholar
Takazawa Y, Maeshima Y, Kitayama H, Yamamoto Y, Kawachi H, Shimizu F, Matsui H, Sugiyama H, Yamasaki Y, Makino H: Infusion of angiotensin-II reduces loss of glomerular capillary area in the early phase of anti-Thy-1 nephritis possibly via regulating angiogenesis-associated factors. Kidney Int. 2005, 68: 704-722. 10.1111/j.1523-1755.2005.00449.x.
Article
CAS
PubMed
Google Scholar
Hirokoshi K, Maeshima Y, Kobayashi K, Matsuura E, Sugiyama H, Yamasaki Y, Masuyama H, Hiramatsu Y, Makino H: Increase of serum angiopoietin-2 during pregnancy is suppressed in women with preeclampsia. Am J Hypertens. 2005, 18: (9 Pt 1):1181-8. 10.1016/j.amjhyper.2005.03.745.
Article
PubMed
CAS
Google Scholar
Lim HS, Lip GY, Blann AD: Angiopoietin-1 and angiopoietin-2 in diabetes mellitus: relationship to VEGF, glycaemic control, endothelial damage/dysfunction and atherosclerosis. Atherosclerosis. 2005, 180: 113-118. 10.1016/j.atherosclerosis.2004.11.004.
Article
CAS
PubMed
Google Scholar
Lee S, Kim W, Moon SO, Sung MJ, Kim DH, Kang KP, Jang KY, Lee SY, Park BH, Koh GY, Park SK: Renoprotective effect of COMP-angiopoietin-1 in db/db mice with type 2 diabetes. Nephrol Dial Transplant. 2007, 22: 396-408. 10.1093/ndt/gfl598.
Article
CAS
PubMed
Google Scholar
Carmeliet P: Mechanisms of angiogenesis and arteriogenesis. Nat Med. 2000, 6: 389-395. 10.1038/74651.
Article
CAS
PubMed
Google Scholar
Wu Q, Du Y, Yang N, Liang Y, Li Y: Microvasculature change and placenta growth factor expression in the early stage of a rat remnant kidney model. Am J Nephrol. 2006, 26: 97-104. 10.1159/000092032.
Article
CAS
PubMed
Google Scholar
O'Reilly MS, Holmgren L, Shing Y, Chen C, Rosenthal RA, Moses M, Lane WS, Cao Y, Sage EH, Folkman J: Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma [see comments]. Cell. 1994, 79: 315-328. 10.1016/0092-8674(94)90200-3.
Article
PubMed
Google Scholar
Basile DP, Fredrich K, Weihrauch D, Hattan N, Chilian WM: Angiostatin and matrix metalloprotease expression following ischemic acute renal failure. Am J Physiol Renal Physiol. 2004, 286: F893-902. 10.1152/ajprenal.00328.2003.
Article
CAS
PubMed
Google Scholar
Mu W, Long DA, Ouyang X, Agarwal A, Cruz PE, Roncal CA, Nakagawa T, Yu X, Hauswirth WW, Johnson RJ: Angiostatin overexpression is associated with an improvement in chronic kidney injury by an anti-inflammatory mechanism. Am J Physiol Renal Physiol. 2009, 296: F145-152. 10.1152/ajprenal.90430.2008.
Article
PubMed Central
CAS
PubMed
Google Scholar
Hudson BG, Reeders ST, Tryggvason K: Type IV collagen: structure, gene organization, and role in human diseases. Molecular basis of Goodpasture and Alport syndromes and diffuse leiomyomatosis. J Biol Chem. 1993, 268: 26033-26036.
CAS
PubMed
Google Scholar
Maeshima Y, Colorado PC, Torre A, Holthaus KA, Grunkemeyer JA, Ericksen MB, Hopfer H, Xiao Y, Stillman IE, Kalluri R: Distinct antitumor properties of a type IV collagen domain derived from basement membrane. J Biol Chem. 2000, 275: 21340-21348. 10.1074/jbc.M001956200.
Article
CAS
PubMed
Google Scholar
Petitclerc E, Boutaud A, Prestayko A, Xu J, Sado Y, Ninomiya Y, Sarras MP, Hudson BG, Brooks PC: New Functions for Non-collagenous Domains of Human Collagen Type IV. Novel integrin ligands inhibiting angiogenesis and tumor growth in vivo. J Biol Chem. 2000, 275: 8051-8061. 10.1074/jbc.275.11.8051.
Article
CAS
PubMed
Google Scholar
Hamano Y, Zeisberg M, Sugimoto H, Lively JC, Maeshima Y, Yang C, Hynes RO, Werb Z, Sudhakar A, Kalluri R: Physiological levels of tumstatin, a fragment of collagen IV alpha3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via alphaV beta3 integrin. Cancer Cell. 2003, 3: 589-601. 10.1016/S1535-6108(03)00133-8.
Article
PubMed Central
CAS
PubMed
Google Scholar
Maeshima Y, Colorado PC, Kalluri R: Two RGD-independent alpha vbeta 3 integrin binding sites on tumstatin regulate distinct anti-tumor properties. J Biol Chem. 2000, 275: 23745-23750. 10.1074/jbc.C000186200.
Article
CAS
PubMed
Google Scholar
Eikesdal HP, Sugimoto H, Birrane G, Maeshima Y, Cooke VG, Kieran M, Kalluri R: Identification of amino acids essential for the antiangiogenic activity of tumstatin and its use in combination antitumor activity. Proc Natl Acad Sci USA. 2008, 105: 15040-15045. 10.1073/pnas.0807055105.
Article
PubMed Central
CAS
PubMed
Google Scholar
Kalluri R, Sun MJ, Hudson BG, Neilson EG: The Goodpasture autoantigen. Structural delineation of two immunologically privileged epitopes on alpha3(IV) chain of type IV collagen. J Biol Chem. 1996, 271: 9062-9068. 10.1074/jbc.271.15.9062.
Article
CAS
PubMed
Google Scholar
Hellmark T, Burkhardt H, Wieslander J: Goodpasture disease. Characterization of a single conformational epitope as the target of pathogenic autoantibodies. J Biol Chem. 1999, 274: 25862-25868. 10.1074/jbc.274.36.25862.
Article
CAS
PubMed
Google Scholar
Maeshima Y, Manfredi M, Reimer C, Holthaus KA, Hopfer H, Chandamuri BR, Kharbanda S, Kalluri R: Identification of the anti-angiogenic site within vascular basement membrane-derived tumstatin. J Biol Chem. 2001, 276: 15240-15248. 10.1074/jbc.M007764200.
Article
CAS
PubMed
Google Scholar
Maeshima Y, Yerramalla UL, Dhanabal M, Holthaus KA, Barbashov S, Kharbanda S, Reimer C, Manfredi M, Dickerson WM, Kalluri R: Extracellular matrix-derived peptide binds to alpha(v)beta(3) integrin and inhibits angiogenesis. J Biol Chem. 2001, 276: 31959-31968. 10.1074/jbc.M103024200.
Article
CAS
PubMed
Google Scholar
Maeshima Y, Sudhakar A, Lively JC, Ueki K, Kharbanda S, Kahn CR, Sonenberg N, Hynes RO, Kalluri R: Tumstatin, an endothelial cell-specific inhibitor of protein synthesis. Science. 2002, 295: 140-143. 10.1126/science.1065298.
Article
CAS
PubMed
Google Scholar
Kestila M, Lenkkeri U, Mannikko M, Lamerdin J, McCready P, Putaala H, Ruotsalainen V, Morita T, Nissinen M, Herva R, Kashtan CE, Peltonen L, Holmberg C, Olsen A, Tryggvason K: Positionally cloned gene for a novel glomerular protein--nephrin--is mutated in congenital nephrotic syndrome. Mol Cell. 1998, 1: 575-582. 10.1016/S1097-2765(00)80057-X.
Article
CAS
PubMed
Google Scholar
O'Reilly MS, Boehm T, Shing Y, Fukai N, Vasios G, Lane WS, Flynn E, Birkhead JR, Olsen BR, Folkman J: Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell. 1997, 88: 277-285. 10.1016/S0092-8674(00)81848-6.
Article
PubMed
Google Scholar
Yamaguchi N, Anand-Apte B, Lee M, Sasaki T, Fukai N, Shapiro R, Que I, Lowik C, Timpl R, Olsen BR: Endostatin inhibits VEGF-induced endothelial cell migration and tumor growth independently of zinc binding. Embo J. 1999, 18: 4414-4423. 10.1093/emboj/18.16.4414.
Article
PubMed Central
CAS
PubMed
Google Scholar
Hanai J, Dhanabal M, Karumanchi SA, Albanese C, Waterman M, Chan B, Ramchandran R, Pestell R, Sukhatme VP: Endostatin causes G1 arrest of endothelial cells through inhibition of cyclin D1. J Biol Chem. 2002, 277: 16464-16469. 10.1074/jbc.M112274200.
Article
CAS
PubMed
Google Scholar
Hajitou A, Grignet C, Devy L, Berndt S, Blacher S, Deroanne CF, Bajou K, Fong T, Chiang Y, Foidart JM, Noel A: The antitumoral effect of endostatin and angiostatin is associated with a down-regulation of vascular endothelial growth factor expression in tumor cells. Faseb J. 2002, 16: 1802-1804.
CAS
PubMed
Google Scholar
Matsuno H, Yudoh K, Uzuki M, Nakazawa F, Sawai T, Yamaguchi N, Olsen BR, Kimura T: Treatment with the angiogenesis inhibitor endostatin: a novel therapy in rheumatoid arthritis. J Rheumatol. 2002, 29: 890-895.
CAS
PubMed
Google Scholar
Takahashi K, Saishin Y, Silva RL, Oshima Y, Oshima S, Melia M, Paszkiet B, Zerby D, Kadan MJ, Liau G, Kaleko M, Connelly S, Luo T, Campochiaro PA: Intraocular expression of endostatin reduces VEGF-induced retinal vascular permeability, neovascularization, and retinal detachment. Faseb J. 2003, 17: 896-898.
CAS
PubMed
Google Scholar
Tanabe K, Maeshima Y, Ichinose K, Kitayama H, Takazawa Y, Hirokoshi K, Kinomura M, Sugiyama H, Makino H: Endostatin peptide, an inhibitor of angiogenesis, prevents the progression of peritoneal sclerosis in a mouse experimental model. Kidney Int. 2007, 71: 227-238. 10.1038/sj.ki.5002040.
Article
CAS
PubMed
Google Scholar
Cattaneo MG, Pola S, Francescato P, Chillemi F, Vicentini LM: Human endostatin-derived synthetic peptides possess potent antiangiogenic properties in vitro and in vivo. Exp Cell Res. 2003, 283: 230-236. 10.1016/S0014-4827(02)00057-5.
Article
CAS
PubMed
Google Scholar
Sudhakar A, Sugimoto H, Yang C, Lively J, Zeisberg M, Kalluri R: Human tumstatin and human endostatin exhibit distinct antiangiogenic activities mediated by alpha v beta 3 and alpha 5 beta 1 integrins. Proc Natl Acad Sci USA. 2003, 100: 4766-4771. 10.1073/pnas.0730882100.
Article
PubMed Central
CAS
PubMed
Google Scholar
Karumanchi SA, Jha V, Ramchandran R, Karihaloo A, Tsiokas L, Chan B, Dhanabal M, Hanai JI, Venkataraman G, Shriver Z, Keiser N, Kalluri R, Zeng H, Mukhopadhyay D, Chen RL, Lander AD, Hagihara K, Yamaguchi Y, Sasisekharan R, Cantley L, Sukhatme VP: Cell surface glypicans are low-affinity endostatin receptors. Mol Cell. 2001, 7: 811-822. 10.1016/S1097-2765(01)00225-8.
Article
CAS
PubMed
Google Scholar
Nakashima T, Hirano S, Agata N, Kumagai H, Isshiki K, Yoshioka T, Ishizuka M, Maeda K, Takeuchi T: Inhibition of angiogenesis by a new isocoumarin, NM-3. J Antibiot (Tokyo). 1999, 52: 426-428. 10.7164/antibiotics.52.426.
Article
CAS
Google Scholar
Reimer CL, Agata N, Tammam JG, Bamberg M, Dickerson WM, Kamphaus GD, Rook SL, Milhollen M, Fram R, Kalluri R, Kufe D, Kharbanda S: Antineoplastic effects of chemotherapeutic agents are potentiated by NM-3, an inhibitor of angiogenesis. Cancer Res. 2002, 62: 789-795.
CAS
PubMed
Google Scholar
Agata N, Nogi H, Bamberg M, Milhollen M, Pu M, Weitman S, Kharbanda S, Kufe D: The angiogenesis inhibitor NM-3 is active against human NSCLC xenografts alone and in combination with docetaxel. Cancer Chemother Pharmacol. 2005, 56: 610-614. 10.1007/s00280-005-1013-4.
Article
CAS
PubMed
Google Scholar
Wang JJ, Zhang SX, Lu K, Chen Y, Mott R, Sato S, Ma JX: Decreased expression of pigment epithelium-derived factor is involved in the pathogenesis of diabetic nephropathy. Diabetes. 2005, 54: 243-250. 10.2337/diabetes.54.1.243.
Article
CAS
PubMed
Google Scholar
Wang JJ, Zhang SX, Mott R, Chen Y, Knapp RR, Cao W, Ma JX: Anti-inflammatory effects of pigment epithelium-derived factor in diabetic nephropathy. Am J Physiol Renal Physiol. 2008, 294: F1166-1173. 10.1152/ajprenal.00375.2007.
Article
CAS
PubMed
Google Scholar
Watanabe K, Hasegawa Y, Yamashita H, Shimizu K, Ding Y, Abe M, Ohta H, Imagawa K, Hojo K, Maki H, Sonoda H, Sato Y: Vasohibin as an endothelium-derived negative feedback regulator of angiogenesis. J Clin Invest. 2004, 114: 898-907.
Article
PubMed Central
CAS
PubMed
Google Scholar
Yamashita H, Abe M, Watanabe K, Shimizu K, Moriya T, Sato A, Satomi S, Ohta H, Sonoda H, Sato Y: Vasohibin prevents arterial neointimal formation through angiogenesis inhibition. Biochem Biophys Res Commun. 2006, 345: 919-925. 10.1016/j.bbrc.2006.04.176.
Article
CAS
PubMed
Google Scholar
Shen J, Yang X, Xiao WH, Hackett SF, Sato Y, Campochiaro PA: Vasohibin is up-regulated by VEGF in the retina and suppresses VEGF receptor 2 and retinal neovascularization. Faseb J. 2006, 20: 723-725.
CAS
PubMed
Google Scholar
Yoshinaga K, Ito K, Moriya T, Nagase S, Takano T, Niikura H, Yaegashi N, Sato Y: Expression of vasohibin as a novel endothelium-derived angiogenesis inhibitor in endometrial cancer. Cancer Sci. 2008, 99: 914-919. 10.1111/j.1349-7006.2008.00777.x.
Article
CAS
PubMed
Google Scholar
Miyake K, Nishida K, Kadota Y, Yamasaki H, Nasu T, Saitou D, Tanabe K, Sonoda H, Sato Y, Maeshima Y, Makino H: Inflammatory cytokine-induced expression of vasohibin-1 by rheumatoid synovial fibroblasts. Acta Med Okayama. 2009, 63: 349-358.
CAS
PubMed
Google Scholar
Kimura H, Miyashita H, Suzuki Y, Kobayashi M, Watanabe K, Sonoda H, Ohta H, Fujiwara T, Shimosegawa T, Sato Y: Distinctive localization and opposed roles of vasohibin-1 and vasohibin-2 in the regulation of angiogenesis. Blood. 2009
Google Scholar
Kosugi T, Nakayama T, Li Q, Chiodo VA, Zhang L, Campbell-Thompson M, Grant M, Croker BP, Nakagawa T: Soluble Flt-1 gene therapy ameliorates albuminuria but accelerates tubulointerstitial injury in diabetic mice. Am J Physiol Renal Physiol. 298: F609-616. 10.1152/ajprenal.00377.2009.
Nangaku M: Chronic hypoxia and tubulointerstitial injury: a final common pathway to end-stage renal failure. J Am Soc Nephrol. 2006, 17: 17-25. 10.1681/ASN.2005070757.
Article
CAS
PubMed
Google Scholar
Heishi T, Hosaka T, Suzuki Y, Miyashita H, Oike Y, Takahashi T, Nakamura T, Arioka S, Mitsuda Y, Takakura T, Hojo K, Matsumoto M, Yamauchi C, Ohta H, Sonoda H, Sato Y: Endogenous angiogenesis inhibitor vasohibin1 exhibits broad-spectrum antilymphangiogenic activity and suppresses lymph node metastasis. Am J Pathol. 176: 1950-1958. 10.2353/ajpath.2010.090829.