Figure 8
From: Toll-like receptor 2 agonists inhibit human fibrocyte differentiation
TLR2 agonists do not inhibit the differentiation of purified monocytes to fibrocytes. Human monocytes were cultured in SFM for 5 days in the presence of LPS (1 μg/ml), PGN (2 μg/ml), Pam3CSK4 (1 μg/ml), HKLM (1 × 108 cells/ml), LM-MS (1 μg/ml), PG-LPS (10 μg/ml), LTA (2 μg/ml) and FSL-1 (1 μg/ml). The results are means ± SEM of fibrocytes per 2.5 × 105 PBMCs (n = 4 separate experiments). *P < 0.05 compared to control (one-way ANOVA, Dunnett's test).