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Table 2 Composition of interstitial fluid in tumors

From: Interstitial fluid: the overlooked component of the tumor microenvironment?

Tumor type Host Protein, mg/ml COP, mm Hg pH Lactic acid, mg/l Reference
   TIF Subcutis Plasma TIF Subcutis Plasma TIF Plasma (arterial) TIF Plasma  
Carcinoma (Walker 256) Rat 32 ± 1 41 ± 2 48 ± 1     7.044 ±0.044 7.313 ± 0.041 16.1 ± 1.1 9.5 ± 0.9 [41, 95]
Mammary carcinoma Mouse 54   55 - 60         [40]
Carcinoma (Walker 256) Rat        6.98 ± 0.13   15 15 [70]
Colon adenocarcinoma (LS174T) Mouse     16.7 ± 3.0        [43]
Small cell lung carcinoma (54A)      21.1 ± 2.8 8.2 ±2.3 20.0 ± 1.6      
Mammary carcinoma (chemically induced) Rat 44.7   54.9 16.6 ± 1.0 13.8 ±1.0 20.5 ±0.8      [61]
  1. COP: Colloid osmotic pressure, TIF: Tumor interstitial fluid. Empty cells in table: Value not determined