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Table 1 Summary of cell derived factors in different cell populations.

From: Role of paracrine factors in stem and progenitor cell mediated cardiac repair and tissue fibrosis

Stem cell type Stem-cell derived factors
Bone marrow  
   BM-MNCs VEGF, bFGF, Ang-1, IL-1β, TNF-α [26]
   BMSCs (HSCs and MSCs) VEGF, bFGF, IGF, SDF-1, Akt, eNOS [27]
   MSCs VEGF, bFGF, Ang-1, IL-1, SDF-1, PIGF, MCP-1, FGF-7, IL-6, TGF-β, PDGF, PA, MMP-9, TB4, Sfrp, Tenacin C, Thrombospondin-1 [28, 29]
   MAPCs VEGF, MCP-1, TGF- β, PDGF-BB [32]
   Multipotent BM-derived cells (non-HSCs and non-MSCs) VEGF, bFGF, Ang-1, Ang-2, IGF-1, SDF-1α, PDGF-B, HGF [34]
Circulating  
   Cultured PB-MNCs VEGF, HGF, G-CSF, GM-CSF [35]
   EPCs VEGF-A, VEGF-B, SDF-1, IGF-1 [72]; VEGF-A FGF-2, IGF-1, HGF, Ang-1, SDF-1 [36]
Tissue resident  
   Cardiac stem cells  
   c-kit+, MDR-1+, Sca-1+ IGF-1, HGF [71]
   Adipose stem cells MMP-9, MMP-3 [82]; VEGF, HGF, TGF-β [83, 84]