Figure 4

Molecular characterization of HCV recurrence samples at diagnosis time for disease severity progression prediction. A. Schematic illustration of a retrospective analysis using prospectively collected FFPE liver biopsy samples at HCV recurrence diagnosis (A) and 3-years of follow-up (B) as time-point for classification. B. METAVIR score criteria used for the classification of FFPE liver biopsy samples. Liver biopsy samples at HCV recurrence diagnosis time were classified in three groups (G1, G2, and G3) depending on the fibrosis severity of paired 3-years follow-up biopsy samples. C. Dendrogram illustrating a supervised agglomerative hierarchical clustering with 50 differentially expressed beads identified between G1 vs. G3 using DASL assay.