Table 2 Identification of Integra® (IT) matrix targeting peptides from libraries eluted by acid, acid salt and chondroitin sulfatea
From: A phage-targeting strategy for the design of spatiotemporal drug delivery from grafted matrices
IT1b | R3 (pH 2) | IT6c | R3 (pH 2) | IT6 | R (GAGd) | IT7c | R3 (pH 2) | IT7 | R3 (GAG) |
|---|---|---|---|---|---|---|---|---|---|
BSA | IT1 (Figure 3) | BSAe | IT6-BA (Figure 4A) | BSA | IT6-CG (Figure 4B) | BSA | IT7-BA (Figure 5A) | BSA | IT7-CG (Figure 5B) |
3.2 | CTES APYFC | A-1 | CNPLHRQHC | CG-1 | CLSTSSKSC | BA-1 | HWHDWMWSWRRD | CG-1 | AYYPQNHKSNAE |
3.4 | CPDA NNGNC | A-2 | CFKHSSHQC | CG-2 | CLSTSSKSC | BA-2 | SMWPWYYSQWAR | CG-2 | APQYQHNQATHT |
3.7 | CNMA QT NMC | A-3 | CPPTPLSLC | CG-3 | CLSTSSKSC | BA-3 | TLGDRYSTKHPI | CG-3 | SITWTHHPGALQ |
3.8 | CPNA NLGTC | A-4 | CINASKPLC | CG-4 | CQTSANTQC | BA-4 | SFSTMNTAPGGS | CG-4 | AGLHPRSLESLP |
4.2 | CINS FYAQC | A-5 | CNRMVQPMC | CG-5 | CGVPAGSTC | BA-5 | WYMPWWSAGQAA | CG-5 | HPGNRSLDPLNH |
4.3 | CKSA IS SSC | A-6 | CNLALTQAC | CG-6 | CLSTSSKSC | BA-7 | QKKIRKRPHVKR | CG-6 | LLADTTHHRPWT |
4.4 | CVPQYS SQC | A-7 | CFKHSSHQC | CG-7 | CLSTSSKSC | BA-8 | GAFHKHHHARLI | CG-7 | ATGKPTRLESHV |
4.5 | CQPKAVNHC | A-8 | CQEPRSNAC | CG-8 | CLATKLHNC | BA-9 | WYMPWWSAGQAA | CG-8 | NPSNLYRQPAMT |
4.7 | CPVS PS GAC | A-9 | CPSHHLESC | CG-9 | CLSTSSKSC | BA-10 | WNRSPLPDYGAA | CG-9 | SKAHDISQRQPP |
4.8 | CSNA SRPFC | A-10 | CNPLHRQHC | CG-10 | CDGVSTKHC | BA-11 | SLWQRWFPVLDH | CG-10 | VNRIPGENLSSP |
4.10 | CNPA LS THC | A-11 | CSKTFPVRC | CG-11 | CLSTSSKSC | BA-12 | HWHDWMWSWRRD | CG-11 | AYYPQNHKSNAE |
4.13 | CGKA GLPLC | A-12 | CFKHSSHQC | CG-12 | CLSTSSKSC | BA-13 | DLALRNPTPSDP | CG-12 | SNQPAPALFHQL |
4.14 | CPTHP PFQC | - | - | CG-13 | CIKNPTKYC | BA-14 | SHALPLTWSTAA | CG-13 | YSPASKSPVPSL |
4.15 | CES SAIRYC | AS-1 | CFKHSSHQC | CG-14 | CLSTSSKSC | BA-15 | WHYNSWYRWPVM | CG-14 | SVSVGMKPSPRP |
4.18 | CNNGTS RLC | AS-2 | CFKHSSHQC | CG-15 | CMPSPSLK | - | - | CG-15 | SVSVGMKPSPRP |
4.19 | CPS QTHP TC | AS-3 | CTYPFHASC | - | - | - | - | - | - |
4.20 | CTNQQRHTC | - | - | - | - | - | - | - | - |