Altered monocyte and fibrocyte phenotype and function in scleroderma interstitial lung disease: reversal by caveolin-1 scaffolding domain peptide

Table 1 CSD peptide inhibits monocyte migration toward CXCL12^a

Source	TGFβ	CSD Peptide	Cells/high-power field (Mean ± SD)
Normal	-	-	12.0 ± 3.7
Normal	-	⁺	3.6 ± 1.1
Normal	⁺	-	187.7 ± 30.9
Normal	⁺	⁺	15.9 ± 3.6
SSc	-	-	80.0 ± 8.6
SSc	-	⁺	16.7 ± 4.1

^aCSD, caveolin scaffolding domain; CXCL12, stromal cell-derived factor 1; TGFβ, transforming growth factor β; SSc, systemic sclerosis. These data summarize the results presented in Figure 4.

ISSN: 1755-1536