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  1. Erratum

    Fibrogenesis & Tissue Repair 2015 8:4

    Published on: 14 March 2015

    The original article was published in Fibrogenesis & Tissue Repair 2011 4:9

  2. Research

    Developing an in vitro screening assay platform for evaluation of antifibrotic drugs using precision-cut liver slices

    Precision-cut liver slices present different cell types of liver in a physiological context, and they have been explored as effective in vitro model systems to study liver fibrosis. Inducing fibrosis in the liver...

    Satish Kumar Sadasivan, Nethra Siddaraju, Khaiser Mehdi Khan, Balamuralikrishna Vasamsetti, Nimisha R Kumar, Vibha Haridas, Madhusudhan B Reddy, Somesh Baggavalli, Anup M Oommen and Raghavendra Pralhada Rao

    Fibrogenesis & Tissue Repair 2015 8:1

    Published on: 9 January 2015

  3. Research

    Secreted frizzled related proteins inhibit fibrosis in vitro but appear redundant in vivo

    The pathogenesis of pulmonary fibrosis remains poorly understood. The Wnt signaling pathway regulates fibrogenesis in different organs. Here, we studied the role of two extracellular Wnt antagonists, secreted ...

    Ellen De Langhe, Carolina Aznar-Lopez, Vanessa De Vooght, Jeroen A Vanoirbeek, Frank P Luyten and Rik JU Lories

    Fibrogenesis & Tissue Repair 2014 7:14

    Published on: 2 October 2014

  4. Research

    Impaired Cav-1 expression in SSc mesenchymal cells upregulates VEGF signaling: a link between vascular involvement and fibrosis

    Systemic sclerosis (SSc) is characterized by vascular alteration and fibrosis, the former probably leading to fibrosis via the ability of both endothelial cells and pericytes to differentiate toward myofibrobl...

    Paola Cipriani, Paola Di Benedetto, Daria Capece, Francesca Zazzeroni, Vasiliki Liakouli, Piero Ruscitti, Ilenia Pantano, Onorina Berardicurti, Francesco Carubbi, Edoardo Alesse and Roberto Giacomelli

    Fibrogenesis & Tissue Repair 2014 7:13

    Published on: 15 September 2014

  5. Review

    Lipid mediators in diabetic nephropathy

    The implications of lipid lowering drugs in the treatment of diabetic nephropathy have been considered. At the same time, the clinical efficacy of lipid lowering drugs has resulted in improvement in the cardio...

    Swayam Prakash Srivastava, Sen Shi, Daisuke Koya and Keizo Kanasaki

    Fibrogenesis & Tissue Repair 2014 7:12

    Published on: 3 September 2014

  6. Meeting Report

    Highlights of Keystone symposium ‘Fibrosis: from bench to bedside’

    This report is based on the ‘Fibrosis: from bench to bedside’ symposium from the Keystone Symposia meeting series, Keystone, Colorado, 23 to 28 March 2014. It was a fascinating symposium with high quality talk...

    Judith Jeanette de Haan and Fatih Arslan

    Fibrogenesis & Tissue Repair 2014 7:11

    Published on: 15 August 2014

  7. Research

    HDAC class I inhibitor, Mocetinostat, reverses cardiac fibrosis in heart failure and diminishes CD90+ cardiac myofibroblast activation

    Interstitial fibrosis and fibrotic scar formation contribute to cardiac remodeling and loss of cardiac function in myocardial infarction (MI) and heart failure. Recent studies showed that histone deacetylase (...

    Hikmet F Nural-Guvener, Luidmila Zakharova, James Nimlos, Snjezana Popovic, Diego Mastroeni and Mohamed A Gaballa

    Fibrogenesis & Tissue Repair 2014 7:10

    Published on: 2 July 2014

  8. Research

    Anaphylatoxin C5a modulates hepatic stellate cell migration

    C5a and its cognate receptor, C5a receptor (C5aR), key elements of complement, are critical modulators of liver immunity and fibrosis. However, the molecular mechanism for the cross talk between complement and...

    Dola Das, Mark A Barnes and Laura E Nagy

    Fibrogenesis & Tissue Repair 2014 7:9

    Published on: 30 May 2014

  9. Review

    Lung epithelial stem cells and their niches: Fgf10 takes center stage

    Throughout life adult animals crucially depend on stem cell populations to maintain and repair their tissues to ensure life-long organ function. Stem cells are characterized by their capacity to extensively se...

    Thomas Volckaert and Stijn De Langhe

    Fibrogenesis & Tissue Repair 2014 7:8

    Published on: 8 May 2014

  10. Research

    Antibody therapy can enhance AngiotensinII-induced myocardial fibrosis

    Myocardial fibrosis is a pathological process that is characterized by disrupted regulation of extracellular matrix proteins resulting in permanent scarring of the heart tissue and eventual diastolic heart fai...

    Nicole L Rosin, Alison J Gareau, Devin Betsch, Alec Falkenham, Mryanda J Sopel, Timothy DG Lee and Jean-Francois Légaré

    Fibrogenesis & Tissue Repair 2014 7:6

    Published on: 10 April 2014

  11. Meeting Report

    The 23rd Annual Meeting of the European Tissue Repair Society (ETRS) in Reims, France

    The 23rd Annual Meeting of the European Tissue Repair Society, Reims, France, October 23 to 25, 2013 focused on tissue repair and regenerative medicine covering topics such as stem cells, biomaterials, tissue eng...

    Johannes W Von den Hoff, Magnus S Ågren, Bernard Coulomb, Sabine A Eming and Jean-Jacques Lataillade

    Fibrogenesis & Tissue Repair 2014 7:3

    Published on: 19 February 2014

  12. Research

    Tranilast administration reduces fibrosis and improves fatigue resistance in muscles of mdx dystrophic mice

    Duchenne muscular dystrophy (DMD) is a severe and progressive muscle-wasting disorder caused by mutations in the dystrophin gene that result in the absence of the membrane-stabilising protein dystrophin. Dystr...

    Kristy Swiderski, Michelle Todorov, Stefan M Gehrig, Timur Naim, Annabel Chee, David I Stapleton, René Koopman and Gordon S Lynch

    Fibrogenesis & Tissue Repair 2014 7:1

    Published on: 30 January 2014

  13. Research

    Molecular constituents of the extracellular matrix in rat liver mounting a hepatic progenitor cell response for tissue repair

    Tissue repair in the adult mammalian liver occurs in two distinct processes, referred to as the first and second tiers of defense. We undertook to characterize the changes in molecular constituents of the extr...

    Peter Siig Vestentoft, Peter Jelnes, Jesper B Andersen, Thi Anh Thu Tran, Tenna Jørgensen, Morten Rasmussen, Jette Bornholdt, Lene Melsæther Grøvdal, Charlotte Harken Jensen, Lotte Katrine Vogel, Snorri S Thorgeirsson and Hanne Cathrine Bisgaard

    Fibrogenesis & Tissue Repair 2013 6:21

    Published on: 20 December 2013

  14. Review

    Matrix regulation of idiopathic pulmonary fibrosis: the role of enzymes

    Repairing damaged tissues is an essential homeostatic mechanism that enables clearance of dead or damaged cells after injury, and the maintenance of tissue integrity. However, exaggeration of this process in t...

    Deborah L Clarke, Alan M Carruthers, Tomas Mustelin and Lynne A Murray

    Fibrogenesis & Tissue Repair 2013 6:20

    Published on: 26 November 2013

  15. Review

    Experimental liver fibrosis research: update on animal models, legal issues and translational aspects

    Liver fibrosis is defined as excessive extracellular matrix deposition and is based on complex interactions between matrix-producing hepatic stellate cells and an abundance of liver-resident and infiltrating cell...

    Christian Liedtke, Tom Luedde, Tilman Sauerbruch, David Scholten, Konrad Streetz, Frank Tacke, René Tolba, Christian Trautwein, Jonel Trebicka and Ralf Weiskirchen

    Fibrogenesis & Tissue Repair 2013 6:19

    Published on: 1 October 2013

  16. Review

    The role of mouse strain differences in the susceptibility to fibrosis: a systematic review

    In humans, a number of genetic factors have been linked to the development of fibrosis in a variety of different organs. Seeking a wider understanding of this observation in man is ethically important. There i...

    Louise Walkin, Sarah E Herrick, Angela Summers, Paul E Brenchley, Catherine M Hoff, Ron Korstanje and Peter J Margetts

    Fibrogenesis & Tissue Repair 2013 6:18

    Published on: 25 September 2013

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