Fig. 8
From: Activation of hepatic stellate cell in Pten null liver injury model
Images of cultured HSCs treated with or without sFRP. HSCs isolated from control mice are treated with sFRP on the third day of culture for 1 day (day 1), 3 days (day 3), and 6 days (day 6). sFRP treatment completely blocked the activation of HSCs at D3 and D6. The morphology of HSCs in sFRP-treated cultures did not progress to spindle fiber whereas obvious spindle fiber formation is observed in the vehicle-treated cultures