Table 1 Total and fractionated plasma HA content in wild-type and Has3−/− mice after acute carbon tetrachloride exposure
From: Differential effects of hyaluronan synthase 3 deficiency after acute vs chronic liver injury in mice
Group | <100 kDa (ng/mL) | % of total | 100–300 kDa (ng/mL) | % of total | >300 kDa (ng/mL) | % of total | Total (ng/mL) |
|---|---|---|---|---|---|---|---|
Wild-type mice | |||||||
Oil | 10 | 3 | 247 | 77 | 64 | 20 | 322 |
24 h | 78 | 6 | 917 | 76 | 215 | 18 | 1210 |
48 h | 109 | 7 | 1041 | 68 | 376 | 25 | 1526 |
72 h | 38 | 7 | 330 | 58 | 199 | 35 | 567 |
96 h | 7 | 3 | 135 | 65 | 66 | 32 | 208 |
Has3−/− mice | |||||||
Oil | 6 | 5 | 82 | 71 | 27 | 23 | 115 |
24 h | 34 | 3 | 428 | 75 | 112 | 20 | 574 |
48 h | 48 | 9 | 285 | 54 | 199 | 37 | 532 |
72 h | 26 | 7 | 271 | 67 | 106 | 26 | 403 |
96 h | 26 | 6 | 223 | 50 | 196 | 44 | 445 |