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Fig. 5 | Fibrogenesis & Tissue Repair

Fig. 5

From: Differential effects of hyaluronan synthase 3 deficiency after acute vs chronic liver injury in mice

Fig. 5

Hepatic fibrotic marker transcript accumulation after acute CCl4 exposure. The mice were exposed to CCl4 and euthanized 48 h later. Control animals received an olive oil (oil) injection. Hepatic a. Tgfβ1, b Ctgf, c Acta2, d Col1a1, e Col1a2, and f Serpinh1 were measured using real-time PCR. The data are expressed as fold change over each strain’s olive oil-treated control after normalizing for input cDNA using 18S (n = 6–8 mice per experimental group). *P < 0.05 compared between genotypes at the same time point

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