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Table 7 Venn analysis for pathways of differentially expressed genes belong to both LPS and HMGB1 treatment in JS1 cells vs JS2 cells, and the key regulatory genes

From: Transcriptomic analysis of the effects of Toll-like receptor 4 and its ligands on the gene expression network of hepatic stellate cells

Pathway ID Pathway term Enrichment (+, up; −, down) P value No. of DifGenes Gene-act-net core genes (degree >5)
PATH:03420 Nucleotide excision repair 4.6978 0.0308 3 Pold2
PATH:00010 Glycolysis/gluconeogenesis 4.3364 0.0171 4 Hk1
PATH:03040 Spliceosome 3.5744 0.0052 7 Ddx39b
PATH:04110 Cell cycle 2.7963 0.0403 5 TRP53, Ccnd2
PATH:00230 Purine metabolism 2.4022 0.0476 6 Pde2a, Polr2f, Ak2
PATH:04010 MAPK signaling pathway −3.3387 0.0133 6 Prkca, Map3k1, Hspb1
PATH:04141 Protein processing in endoplasmic reticulum −4.4615 0.0075 5 Eif2s1
PATH:04120 Ubiquitin-mediated proteolysis −5.3857 0.0035 5 Map3k1