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Fig. 1 | Fibrogenesis & Tissue Repair

Fig. 1

From: Dipeptidyl peptidase-4 and kidney fibrosis in diabetes

Fig. 1

Membrane-anchored DPP-4 and soluble DPP-4. Catalytically active DPP-4 is liberated from the plasma membrane to produce a soluble circulating form, sDPP-4, which lacks the intracellular tail and transmembrane regions and accounts for a substantial proportion of DPP-4 activity. In addition to its exopeptidase activity, DPP-4 also functions as a binding protein which can bind with fibronectin and adenosine deaminase (ADA)

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