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Fig. 5 | Fibrogenesis & Tissue Repair

Fig. 5

From: In vitro reversion of activated primary human hepatic stellate cells

Fig. 5

Gene expression changes elicited during the in vitro reversion of human HSC activation. a Heatmap representing the hierarchical clustering of genes significantly differentially regulated between aHSCs, qHSCs, and rHSCs. b Venn diagram showing the number of genes significantly differentially regulated between qHSCs and rHSCs or aHSCs and rHSCs. The intersection of the Venn diagram shows the number of overlapping genes significantly differentially regulated in both comparisons. c List of fold changes (relative to aHSCs) for the top 10 genes upregulated and downregulated in rHSCs (microarray data). d Confirmation of the expression levels of selected top deregulated genes by RTq-PCR. The presented results are from three different donors. **p < 0.01, ***p < 0.001

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