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Fig. 4 | Fibrogenesis & Tissue Repair

Fig. 4

From: Novel approach for the detection of tubular cell migration into the interstitium during renal fibrosis in rats

Fig. 4

Phenotypes of BrdU-positive tubular cells in the UUO kidneys. a Expression of myofibroblast-related markers in kidneys at 7 days after UUO. BrdU (red), markers (green), and DAPI (blue). Magnification, ×1000. Arrowheads indicate BrdU-positive cells coexpressing myofibroblast markers. b Number of alpha-SMA-positive cells and alpha-SMA/BrdU double-positive cells in the interstitium of contralateral and UUO kidneys at 8 days after operation. Values are means ± SE (n = 5). c Expression of AQP-1 in kidneys at 7 days after UUO. Arrowheads indicate BrdU-positive cells losing AQP-1 expression. BrdU (red), AQP-1 (green), and DAPI (blue). Magnification, ×1000. d Expression of inflammatory cell markers in kidneys at 7 days after UUO. DAPI (blue). Magnification, ×1000

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Fibrogenesis & Tissue Repair

ISSN: 1755-1536

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