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Fig. 2 | Fibrogenesis & Tissue Repair

Fig. 2

From: Pentoxifylline immunomodulation in the treatment of experimental chronic pulmonary paracoccidioidomycosis

Fig. 2

PTX treatment significantly reduces pulmonary inflammation and fungal burden and hinders collagen deposition in Pb-infected treated mice. a, d, g, j correspond to photomicrographs of lung sections of a representative Pb-infected mouse at 12 weeks p.i. stained with H&E, Grocott, and PIFG, respectively. b, e, h, k correspond to photomicrographs of lung sections of a representative Pb-infected mouse, treated with PTX at the end of the therapy (12 weeks p.i) stained with H&E, Grocott, and PIFG, respectively. c, f, i, l are histomorphometric quantification graphs of inflammation, nodules, fungal burden, and collagen deposition in the pulmonary lesions of Pb-infected mice treated or not with PTX. n = 5 mice per group at each period of evaluation, *p <0.05

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