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Fig. 1 | Fibrogenesis & Tissue Repair

Fig. 1

From: Pentoxifylline immunomodulation in the treatment of experimental chronic pulmonary paracoccidioidomycosis

Fig. 1

PTX treatment decreases pulmonary density in Pb-infected mice. Representative HRCT images of upper and central pulmonary regions obtained from PBS-inoculated mice (a, b), PBS-inoculated mice treated with PTX (c, d), Pb-infected mice (e, f), and Pb-infected mice treated with PTX (g, h) at 12 weeks. Pulmonary density was measured in the lung parenchyma as described in the “Methods” section and is expressed as the mean of Hounsfield units (HU) ± SEM. i, j correspond to HUs measured in the upper (I) and central (J) lung regions at 0, 4, 8, 12, and 16 weeks. The upper right symbol in (a) gives the spatial position of posterior (P), anterior (A), left (L), and right (R) regions. n = 10 mice per group at each period of evaluation, *p <0.05; **p <0.01; ***p <0.001. ns not significant

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