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Table 2 Covariance analysis of repeated measures for creatinine and estimated glomerular filtration rate

From: Donor caveolin 1 (CAV1) genetic polymorphism influences graft function after renal transplantation

 

Serum creatinine

eGFR (aMDRD)

Variable

Beta

F

P

Beta

F

P

Intercept

0.9319

  

1.8358

  

CAV1 genotype

 

4.93

0.008

 

5.98

0.003

AA

Reference

  

Reference

  

AC

0.0515

  

−0.0508

  

CC

0.0254

  

−0.0310

  

Time (per year)

0.0262

17.63

<0.0001

−0.0298

18.23

<0.0001

Interaction genotype/time (per year)

 

3.88

0.02

 

3.75

0.02

AA

Reference

  

Reference

  

AC

−0.0209

  

0.0230

  

CC

−0.0219

  

0.0249

  

Delayed graft function

 

0.08

0.78

 

0.53

0.47

No

Reference

  

Reference

  

Yes

−0.0956

  

0.1322

  

Interaction genotype/DGF

 

6.02

0.003

 

6.98

0.001

AA

Reference

  

Reference

  

AC

0.0990

  

−0.1287

  

CC

0.1691

  

−0.2123

  

Donor age (per year)

0.0036

84.10

<0.0001

−0.0045

140.76

<0.0001

Acute rejection

  

NS

 

15.15

0.0001

No

   

Reference

  

Yes

   

−0.0695

  
  1. DGF: delayed graft function, eGFR: estimated glomerular filtration rate, aMDRD: abbreviated modification of diet in renal diseases, NS: not significant.