Figure 3
From: Deficient repair response of IPF fibroblasts in a co-culture model of epithelial injury and repair
Immunofluorescence staining showing fibroblast invasion into epithelial scratch wounds. Representative images showing that sub-epithelial normal fibroblasts (NHLF-1 and NHLF-2) transmigrated into the denuded area and filled the wound progressively forming a mechanical barrier preventing re-epithelialization. Fewer IPF fibroblasts (IPF-123A, 147B, and 217B) transmigrated and promoted A549 migration and re-epithelialization. Green: e-cadherin, Red: vimentin, Blue: DAPI.