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Figure 2 | Fibrogenesis & Tissue Repair

Figure 2

From: Medical therapy of stricturing Crohn’s disease: what the gut can learn from other organs - a systematic review

Figure 2

Pipeline for therapeutic strategies to alter and improve fibrosis in organs other than the intestine. Each color represents a particular organ. Agents are classified based on their mode of action. Data derived from Embase, Medline and ClinicalTrials.gov. CCL2, chemokine ligand 2; CTGF, connective tissue growth factor; ECM, extracellular matrix; HIF, hypoxia inducible factor; IL, interleukin; JAK, janus kinase; JNK, c-Jun N-terminal kinase; mAb, monoclonal antibody; SAP, serum amyloid P component; TGF-β, transforming growth factor beta; VIP, vasoactive intestinal peptide.

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Fibrogenesis & Tissue Repair

ISSN: 1755-1536

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