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Figure 2 | Fibrogenesis & Tissue Repair

Figure 2

From: Tranilast administration reduces fibrosis and improves fatigue resistance in muscles of mdx dystrophic mice

Figure 2

Tranilast effects on fibrosis in the diaphragm and TA of mdx mice. At endpoint, the diaphragm muscle of vehicle-treated C57BL/10 (A), vehicle-treated mdx (B), tranilast-treated C57BL/10 (C) or tranilast-treated mdx (D) mice was excised and collagen infiltration visualised in cross-sections after Van Gieson’s staining. (E) Fibrotic accumulation in Van Gieson’s stained sections from diaphragm and tibialis anterior muscles of untreated and treated mice. #P < 0.05 group main effect, mdx vs. control. *P < 0.05 mdx treated vs. mdx control; n.s, not significant.

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Fibrogenesis & Tissue Repair

ISSN: 1755-1536

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