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Figure 1 | Fibrogenesis & Tissue Repair

Figure 1

From: Tranilast administration reduces fibrosis and improves fatigue resistance in muscles of mdx dystrophic mice

Figure 1

Tranilast effects on muscle mass and whole body strength of mdx mice. Three-week-old male C57Bl/10 control mice or mdx mice received either vehicle or tranilast treatment for 9 weeks. (A) Individual muscle masses at the end of the treatment period. (B) Grip strength was measured 3 days prior to endpoint. (C) Whole body function and coordination was assessed by rotarod performance 2 days prior to endpoint. QUAD: quadriceps; GAST: gastrocnemius; TA: tibialis anterior; PLANT: plantaris; EDL: extensor digitorum longus; SOL: soleus. #P < 0.05 group main effect, mdx vs. control.

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Fibrogenesis & Tissue Repair

ISSN: 1755-1536

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