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Figure 4 | Fibrogenesis & Tissue Repair

Figure 4

From: Cyclosporin A reduces matrix metalloproteinases and collagen expression in dermal fibroblasts from regenerative FOXN1 deficient (nude) mice

Figure 4

CsA modulates the expression of collagen I (A and B) and collagen III (C) mRNA in cultured dermal fibroblasts. Quantitative RT-PCR determination of collagen I and III mRNA levels was assessed in cultured CsA treated dermal fibroblasts from nude and wild-type mice. Expression of collagens mRNA was normalized to levels of Hprt1 mRNA in the reaction. The means and standard errors are shown from three experiments, each performed in triplicate (n = 9); (*p < 0.05; ***p < 0.001), relative to control, untreated cells (0 CsA).

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Fibrogenesis & Tissue Repair

ISSN: 1755-1536

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