Table 2 Genes with ≥1.5-fold difference and P <0.05 compared to 0 Gy on day 21 and 56 post-irradiation

adamts5

-

-

−1.58

-

-

cdh3

-

-

−2.49

-

-

cd44

-

1.94

-

1.88

1.67

col1a1

1.82

2.40

2.28

2.52

1.58

col4a3

-

-

-

1.69

1.61

col5a1

-

-

-

1.81

1.60

fn1

-

-

-

1.53

-

hapln1

-

1.96

-

-

1.87

itga2

-

1.51

-

1.57

-

itga3

-

-

-

1.61

-

Itgav

-

1.63

-

1.53

1.57

Itgax

-

-

-

1.53

-

lama2

1.71

-

-

-

-

lama3

-

-

-

1.77

-

lamb3

-

1.62

-

-

1.79

mmp2

-

-

−1.62

-

-

mmp7

−2.46

-

-

-

-

mmp11

-

-

-

1.87

mmp14

1.61

1.63

1.62

1.94

1.59

mmp15

1.50

1.66

1.61

1.96

1.78

ncam2

-

-

-

2.11

-

selp

-

-

-

1.56

1.56

tgfbi

-

-

-

-

−1.50

timp1

1.59

1.89

-

-

-

timp3

-

2.44

-

1.98

-

tnc

-

1.75

-

1.61

-

Total (26)

6

11

6

16

12

Day 56

2 Gy photons

2 Gy protons

LDR

LDR + 2 Gy photons

LDR + 2 Gy protons

adamts1

-

-

-

1.57

-

cdh1

-

-

-

1.71

-

cdh3

2.97

4.02

-

3.98

-

cd44

-

1.66

-

-

-

col1a1

-

1.67

-

-

2.31

col4a3

1.64

-

-

1.69

-

ctgf

-

-

-

1.70

-

itga2

1.54

1.72

-

-

-

itga4

−1.63

-

−1.82

−1.52

−2.09

itgax

-

1.55

-

-

-

itgb4

-

1.86

1.74

-

1.71

lama2

-

-

-

1.74

-

lamb3

-

1.58

-

-

-

lamc1

-

1.60

-

-

-

mmp8

-

-

-

1.76

-

mmp13

-

-

-

-

−2.21

mmp14

1.55

1.75

-

-

1.66

mmp15

1.54

1.79

-

-

1.56

ncam1

-

1.94

-

-

-

ncam2

2.41

-

-

3.6

-

pecam1

-

-

-

3.46

-

sele

-

-

1.57

-

-

sell

-

-

-

-

−1.94

tgfbi

-

1.56

-

-

-

timp3

3.70

4.00

-

4.10

-

tnc

-

1.56

-

-

-

Total (26)

8

14

3

11

7