The role of mouse strain differences in the susceptibility to fibrosis: a systematic review

Table 1 Summary of the various types of organ fibrosis and associated mouse strain susceptibility

Strain	Susceptibility	Fibrosis type	Reference
C57BL/6J	Susceptible	Pulmonary	[7]
		Hepatic	[20]
		Renal	[8]
	Resistant	Hepatic	[21]
C57BL/6	Susceptible	Pulmonary	[22]
		Intestinal	[23, 24]
		Hepatic	[25]
		Renal	[26]
	Intermediate	Hepatic	[21]
	Resistant	Renal	[27]
		Cardiac	[28]
		Cardiac	[29]
BALB/c	Susceptible	Hepatic	[21]
	Resistant	Pulmonary	[22]
		Hepatic	[25]
		Renal	[26]
BALB/cJ	Susceptible	Hepatic	[20]
C3Hf/Kam	Resistant	Pulmonary	[30]
C3Hf/Kam	Resistant	Intestinal	[23, 24]
C3H/HeJ	Intermediate	Hepatic	[20]
A/J	Susceptible	Cardiac	[29]
	Resistant	Hepatic	[20]
	Resistant	Pulmonary	[31]
DBA/2	Intermediate	Pulmonary	[22]
DBA/2J	Intermediate	Hepatic	[20]
MRL/MpJ	Resistant	Renal	[32]
	Resistant	Cardiac	[33]
	Susceptible	Cardiac	[34]
MRL/MpJ ^lpr/lpr	Susceptible	Renal	[32]
129S1/SvJM	Susceptible	Renal	[8]
129Sv	Resistant	Renal	[27]
129S3	Susceptible	Renal	[28]
Swiss	Intermediate	Pulmonary	[22]
AKR/J	Resistant	Hepatic	[20]
CD1	Susceptible	Renal	[27]
CD1	Susceptible	Renal	[28]
FVB/NJ	Resistant	Hepatic	[20]
Col4A3 ^-/-	Susceptible	Renal	[32]

ISSN: 1755-1536