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Table 4 Differentially expressed genes between cultured fibroblasts and directly isolated myofibroblasts

From: Direct isolation of myofibroblasts and fibroblasts from bleomycin-injured lungs reveals their functional similarities and differences

Gene

Fold change

Col1a1

0.32

Col1a2

0.23

Col3a1

0.06

P4ha3

0.23

Adamts2

0.16

Ccl2

0.03

Ccl5

0.23

Ccl7

0.09

Ccl11

0.002

Cxcl1

0.01

Cxcl2

0.01

Cxcl5

0.01

Cxcl10

0.01

Cxcl14

0.31

  1. Differentially expressed genes in cultured fibroblasts (α-SMA-positive myofibroblast-like cells) relative to directly isolated myofibroblasts by a factor of > 2.0 or < 0.5 and P < 0.05. QRT-PCR was performed in triplicate using three independently prepared RNA samples. Results represent the mean of three experiments.