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Figure 1 | Fibrogenesis & Tissue Repair

Figure 1

From: Platelet-derived growth factor alpha and beta receptors have overlapping functional activities towards fibroblasts

Figure 1

Schematic diagram showing PDGFR-PDGF interactions in vitro: PDGF ligand dimers bind either PDGFRα or PDGFRβ homodimers or the α/β heterodimer. Arrows show proven in vitro ligand-receptor interactions. Each PDGF receptor has five extracellular immunoglobulin-like domains and two intracellular tyrosine kinase domains. PDGFR chains are shown in blue (PDGFRα) and red (PDGFRβ). PDGF ligands are shown in green (PDGF-A), yellow (PDGF-B), orange (PDGF-C) and purple (PDGF-D).

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Fibrogenesis & Tissue Repair

ISSN: 1755-1536

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