From: Fibrosis in systemic sclerosis: common and unique pathobiology
Cytokines |
---|
TGF-β |
IL-4 |
IL-13 |
IL-17 |
IL-33 |
Growth factors, peptides and bioactive lipids |
Wnt family (Wnt3a, Wnt10b, others) |
CTGF (matricellular protein) |
PDGF |
IGFBP-5 |
Endothelin-1 |
Adenosine |
Lysophosphatidic acid (LPA) |
Prostaglandin F |
Chemokines |
CXCL12 |
MCP-1 |
Autoantibodies |
Antibody to Topo I |
Anti-fibroblast antibody |
Anti-PDGF antibody |