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Table 1 Intracellular signal mediators showing aberrant expression in SSc

From: Fibrosis in systemic sclerosis: common and unique pathobiology

Molecule Increased expression/activity Decreased expression/activity
Egr-1, Egr-2  
Sp1  
p300/CBP  
Fli-1  
Smad7  
Ski/Sno  
Nab2  
PTEN  
PPAR-gamma  
microRNA29