Figure 2
From: Heat shock protein 27 (HSP27): biomarker of disease and therapeutic target
HSP27 overexpression was associated with decreased fibrosis after UUO. Tissue sections prepared from 14 day UUO kidneys from wild type and KAP2-HSP27 transgenic mice were stained with trichrome aniline blue and quantitatively analyzed using the Nuance digital analysis software system. Trichrome blue staining was significantly reduced in the transgenic obstructed mice as compared to wild-type mice (P < 0.01). The data shown are representative of the group averages (n = 3 in each group).