Figure 5

Relative change of proteins involved in splice site selection. The relative change of proteins involved in splice site selection and splicing factors following TGF-β₁ stimulation (10 ng/mL) was calculated. The result, when comparing the relative expression between every protein, is visualized as a color grid. Black box represents no statistically significant difference and light grey represents a significant difference of at least P <0.05. 1a denotes: RNA-binding region containing protein 2, 1b: splicing factor, proline-and-glutamine-rich (PTB-associated splicing factor, 1c: splicing factor 3 subunit 1, 1d: splicing factor 3A subunit 3, 1e: splicing factor 3B subunit 1, 1f: U2 small nuclear ribonucleoprotein auxiliary factor 35 Kda subunit related-protein 2, 1 g: splicing factor 3A subunit 2, 1 h: polyadenylate-binding protein 4, 1i: 54 Kda nuclear RNA- and DNA-binding protein (P54(Nrb)), 1j: FUSE binding protein 2, 1 k: splicing factor 3B subunit 3 (spliceosome associated protein 130), and 1 l: splicing factor 3B subunit 793. 2a denotes: splicing factor, arginine/serine-rich 1 (ASF-1), 2b: splicing factor, arginine/serine-rich 7 (splicing factor 9 G8, 2c: splicing factor, arginine/serine-rich 3 (pre-Mrna splicing factor SRP20), 2d: splicing factor U2AF 35 splicing factor U2AF 35 Kda subunit (U2 auxiliary factor 35 Kda subunit), 2e: splicing factor U2AF 65 Kda subunit, 2f: splicing factor, arginine/serine-rich 9 (pre-Mrna splicing factor SRP30c), 2 g: splicing factor, arginine/serine-rich 6 (pre-Mrna splicing factor SRP55), 2 h: splicing factor, arginine/serine-rich 4 (pre-Mrna splicing factor SRP75), 2i: splicing factor arginine/serine-ich 5 (HRS) (pre-Mrna splicing factor SRP40).