Figure 5

Highly related genes and corresponding annotations in fibrotic lesions of combined pulmonary fibrosis and emphysema. Two-dimensional view maps of the relationships between highly related genes and their corresponding annotations in fibrotic lesions of combined pulmonary fibrosis and emphysema (CPFE) using the Gene Functional Classification Tool (http://david.abcc.ncifcrf.gov/gene2gene.jsp) from the Database for Annotation, Visualization and Integrated Discovery (DAVID;http://david.abcc.ncifcrf.gov/home.jsp). Individual gene names in the gene group are listed on the right-hand side of the map and functional annotation terms are presented on the lower side of the map. Annotation cluster 1 for immunoglobulin-like molecules, annotation cluster 2 for immunoglobulin heavy constant region, annotation cluster 3 for immunoglobulin variable region, annotation cluster 4 for structural constituent of cytoskeleton, and annotation cluster 5 for cell adhesion. Green rectangle, corresponding gene-annotation association positively reported in DAVID; black rectangle, corresponding gene-annotation association not yet reported in DAVID.