Amino acid sequence of yeast ERV1 and mouse ALR. Homology between the yeast and mouse proteins is shown by boxed amino acids. Red letters show amino acid sequences of the proteins identified originally [19, 24] with no mitochondrial targeting sequence. These proteins, however, were found to be functionally active in augmenting liver regeneration (ALR) and maintaining cell viability (ERV1). Black letters added to the original sequences show the physiologically produced proteins that can be imported into mitochondria.