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Figure 3 | Fibrogenesis & Tissue Repair

Figure 3

From: Thrombospondin 1 is a key mediator of transforming growth factor β-mediated cell contractility in systemic sclerosis via a mitogen-activated protein kinase kinase (MEK)/extracellular signal-regulated kinase (ERK)-dependent mechanism

Figure 3

Knockdown thrombospondin 1 (TSP1) expression through small interfering (si)RNA transfection alters the contractile characteristics and protein expression in both normal and systemic sclerosis (SSc) fibroblasts. (a) The contractile ability of SSc and normal fibroblasts were reduced following siRNA transfection. (b) Western blot demonstrating a reduction in protein expression following siRNA transfection.

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Fibrogenesis & Tissue Repair

ISSN: 1755-1536

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