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Table 4 Clinical characteristics of patients with emphysema score (ES) > 2 based on type of emphysema.

From: Centrilobular emphysema combined with pulmonary fibrosis results in improved survival

Variable ES > 2
Paraseptal
(n= 7)
ES > 2
Mixed
(n= 8)
ES > 2
Centrilobular
(n= 13)
P value
Age years; median [1st, 3rd] 57 [51, 63] 59 [57, 63] 54 [49, 62] NS*
Gender:     




Male, n 7 8 2 < 0.001




Female, n 0 0 11  
Race:     




Caucasian, n 3 6 7  




African-American, n 3 2 6 NS




Other, n 1 0 0  
Smoking packs/years; median [1st, 3rd] 14 [0, 38] 40 [38, 46] 45 [25, 60] < 0.05*
Right heart catheterization:     




Performed, n (%) 5 (71) 6 (75) 6 (46) NS




Mean PAP mm Hg; median [1st, 3rd] 32 [21, 34] 31 [29, 33] 25 [22, 31] NS*
Surgical lung biopsy:     




Performed, n (%) 6 (86) 5 (63) 9 (70) NS




UIP, n 6 4 4 < 0.05




Fibrotic NSIP, n 0 1 5  
FVC % predicted; median, [1st, 3rd] 57 [50, 60] 59 [51, 63] 71 [58, 84] NS*
TLC % predicted; median, [1st, 3rd] 58 [51, 64] 60 [52, 69] 72 [64, 86] 0.05
DLCO % predicted; median, [1st, 3rd] 25 [21, 31] 28 [23, 34] 27 [18, 37] NS*
  1. *Kruskal-Wallis one-way ANOVA; Chi-square test.
  2. Paraseptal, paraseptal emphysema; mixed, mixed centrilobular and paraseptal emphysema; centrilobular, centrilobular emphysema; mean PAP, mean pulmonary artery pressure; UIP, usual interstitial pneumonia; NSIP, non-specific interstitial pneumonia; FVC, forced vital capacity; TLC, total lung capacity; DLCO, diffusing capacity for carbon monoxide; NS, not significant (P > 0.05).