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Table 3 Pulmonary function tests (PFTs)

From: Centrilobular emphysema combined with pulmonary fibrosis results in improved survival

Variable

ES 0

(n= 48)

0 < ES ≤ 2

(n= 26)

ES > 2

(n = 28)

*P value

FEV1 % predicted; median [1st, 3rd]

53 [43, 74]

59 [48, 77]

66 [60, 76]

NS

FVC % predicted; median [1st, 3rd]

47 [38, 63]

50 [43, 62]

60 [55, 73]

< 0.01

FEV1/FVC ratio median [1st, 3rd]

84 [81, 88]

87 [80, 89]

81 [72, 86]

< 0.05

TLC % predicted; median [1st, 3rd]

44 [39, 57]

50 [44, 59]

64 [57, 73]

<.001

DLCO, % predicted; median [1st, 3rd]

28 [19, 34]

31 [20, 36]

27 [20, 37]

NS

  1. *Kruskal-Wallis one-way ANOVA ES, emphysema score; FEV1, forced expiratory volume in one second; FVC, forced vital capacity; TLC, total lung capacity; DLCO, diffusing capacity for carbon monoxide; NS, not significant (P > 0.05).