Differences in survival among subgroups of patients with advanced emphysema (ES > 2) based on emphysema type. (A) Median survival differed among the three groups (P < 0.01; Kruskal-Wallis one-way ANOVA). By Dunn's multiple comparison tests, patients with centrilobular emphysema (n = 13) or mixed emphysema (n = 8) had a longer survival than patients with paraseptal emphysema (n = 7)(P < 0.01 and P < 0.05, respectively). There was no difference in survival between the centrilobular group and the mixed emphysema group. (B) Kaplan-Meier survival curves of these subgroups of patients revealed a significantly longer survival for the centrilobular and mixed emphysema patients (P < 0.001, log-rank test).