From: Cooperative interaction of CTGF and TGF-β in animal models of fibrotic disease
Treatment | Degree of liver fibrosis (score) | ||||
---|---|---|---|---|---|
None (0) | Minimal (1) | Minimal to mild (2) | Mild (3) | Moderate (4) | |
Vehicle | 9 | 0 | 0 | 0 | 0 |
TGF-β2 | 8 | 0 | 0 | 0 | 0 |
CTGF | 6 | 0 | 0 | 0 | 0 |
TGF-β2 + CTGF | 0 | 4 | 2 | 1 | 1 |
TGF-β2 + CTGF + FG-3019 | 6 | 2 | 0 | 0 | 0 |