Table 1 Hydroxyproline:proline ratio by treatment group and organ in the TGF-β/CTGF synergy model

-

TGF-β2

-

TGF-β2

TGF-β2

-

-

CTGF

CTGF

CTGF

-

-

-

-

FG-3019

Kidney

0.057 ± 0.001

0.061 ± 0.002

0.059 ± 0.001

0.094 ± 0.0051

0.085 ± 0.003^1,3

Liver

0.015 ± 0.001

0.017 ± 0.001

0.016 ± 0.002

0.039 ± 0.003¹

0.032 ± 0.002^1,4

Lung

0.079 ± 0.002

0.078 ± 0.002

0.083 ± 0.001

0.088 ± 0.001²

0.083 ± 0.002^,3

Heart

0.041 ± 0.001

0.044 ± 0.002

0.046 ± 0.002

0.055 ± 0.002¹

0.053 ± 0.003¹