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Figure 1 | Fibrogenesis & Tissue Repair

Figure 1

From: Animal models for investigating chronic pancreatitis

Figure 1

Role of pancreatic stellate cells (PSCs) in fibrosis. Activation of PSCs from a quiescent into a myofibroblast-like type and proliferation occurs via several triggers and is perpetuated in an autocrine loop. Development of fibrosis is a complex process that requires interaction of collagen and extracellular matrix production together with chemokine synthesis and phagocytosis.

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