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Table 2 Genotype distribution of BOSpos and BOSneg patients and healthy controlsa

From: A genetic polymorphism in the CAV1 gene associates with the development of bronchiolitis obliterans syndrome after lung transplantation

   

BOSpos (n= 20)

BOSneg (n= 87)b

Controls (n= 422)

SNPs

Gene region

Major/minor

AA

AB

BB

AA

AB

BB

AA

AB

BB

rs12154695

Unknown

C/A

12 (60)

6 (30)

2 (10)

34 (39)

47 (54)

6 (7)

181 (43)

189 (45)

52 (12)

rs10256914

Intron

T/C

12 (60)

6 (30)

2 (10)

50 (57)

29 (33)

8 (9)

228 (54)

158 (37)

36 (9)

rs3807989 c

Intron

C/T

4 (20)

9 (45)

7 (35)

33 (38)

47 (54)

7 (8)

144 (34)

206 (49)

72 (17)

rs3807994

Intron

C/T

10 (50)

7 (35)

3 (15)

57 (66)

28 (32)

2 (2)

240 (57)

156 (37)

26 (6)

  1. aAll data are n (%). BOSpos, bronchiolitis obliterans syndrome-positive; BOSneg, bronchiolitis obliterans syndrome-negative; A, major; B, minor. bCAV1 genotyping failed in three BOSneg patients. cGenotype distribution BOSpos vs BOSneg: P = 0.015; allele frequency BOSpos vs BOSneg: P = 0.027.