Assessment of proteolytic degradation of the basement membrane: a fragment of type IV collagen as a biochemical marker for liver fibrosis

Table 3 Analyte stability in three rat and three human serum samples in ten freeze-thaw cycles^a

Analyte stability	Percentage recovery compared to 1 × freeze-thaw cycle
Freeze-thaw cycles	Human CO4-MMP	Rat CO4-MMP
2 ×	109.9	81.6
3 ×	75.4	88.9
4 ×	95.6	101.8
5 ×	113.1	85.3
6 ×	92.2	71.1
7 ×	122.6	92.1
8 ×	131.0	83.6
9 ×	104.3	91.0
10 ×	90.9	96.6

^aAll data shown are percentage recovery compared to day 0 or day 1 freeze-thaw cycle.

ISSN: 1755-1536