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Figure 2 | Fibrogenesis & Tissue Repair

Figure 2

From: Assessment of proteolytic degradation of the basement membrane: a fragment of type IV collagen as a biochemical marker for liver fibrosis

Figure 2

Assay characterization. Characterization of the 1438'GTPSVDHGFL'1447 (CO4-MMP) assay with regard to reactivity against intact type IV collagen (CO4 intact), type IV collagen cleaved by pepsin (CO4/pepsin), type IV collagen cleaved by matrix metalloproteinase 2 (CO4/MMP-2), type IV collagen cleaved by MMP-9 (CO4/MMP-9), type IV collagen cleaved by MMP-9 and pepsin, elongated peptide with extension of one amino acid at the neoepitope site, type I collagen cleaved by MMP-9 (CO1/MMP-9) and type VI collagen cleaved by MMP-9 (CO6/MMP-9).

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