Table 3 Regulators of fibronectin (FN) mRNA expression and assembly

Positive regulators of FN mRNA

   TGF-β1 and the TGF-β family

[212, 253–255]

   Platelet-derived growth factor-BB

[256]

   Insulin-like growth factor-1

[256]

   Hepatocyte growth factor

[257]

   Glucose

[258, 259]

   Glucocorticoids

[260]

Negative regulators of FN mRNA

   Cell contractility inhibitor

[3, 121]

   RhoA inhibitors

[165–167]

Positive regulators of FN assembly

   Sphingosine-1-phosphate

[261]

   Estrogen

[262]

   Plasminogen activator inhibitor type I

[263, 264]

   Urokinase plasminogen receptor

[265]

   Connective tissue growth factor

[266]

   Lipoprotein A

[165, 167]