Skip to main content

Table 2 Fibronectin (FN)-binding integrins.

From: Plasma and cellular fibronectin: distinct and independent functions during tissue repair

FN receptor Supports fibrillogenesis Domain References
α3β1 + 70-kDa [63, 146]
α4β1 + IIICS (V) CS1 region and EIIIA [63, 146]
α5β1 + FNIII9-10 (RGD) [22, 60, 143, 144, 251]
α9β1 - EIIIA [65]
α8β1 - FNIII10 (RGD) [63, 64]
αvβ1 - FNIII10 (RGD) [63, 64]
αvβ3 + FNIII10 (RGD) or possibly 70-kDa [139, 143, 144]
αvβ6 + FNIII10 (RGD) [63]
αIIbβ3 + FNIII9-10 (RGD) [38, 63, 145, 252]
  1. + = Has been reported to be involved in FN fibrillogenesis.
  2. - = Has been reported to be involved in adhesion to FN but not fibrillogenesis.