Local apoptosis promotes collagen production by monocyte-derived cells in transforming growth factor β1-induced lung fibrosis

Table 1 Characteristics of subjects

	UIP/IPF, N = 7	CTD-ILD, N = 11	Controls, N = 8	P value
Age, years	74.14 ± 2.132	55.73 ± 4.673	64.25 ± 18.0	NS
Sex, female	3/7	6/11	6/8	NS
Race:
Caucasian	7	7	6
African-American	0	2	0
Asian	0	2	2
Disease subtype:
SSc-ILD (NSIP pattern based on CT scan)	N/A	6/11	N/A
AMAS-UIP pattern (biopsy proven)		5/11
Known pulmonary hypertension	0/9	0/11	N/A	N/A
FVC, percentage of predicted	70.86 ± 2.492	60.70 ± 4.410	N/A	NS
DLCO, percentage of predicted	55.29 ± 5.643	56.82 ± 5.220	N/A	N/A

AMAS = amyopathic antisynthetase syndrome; CT = computed tomography; CTD = connective tissue disease; DLCO = diffusing capacity of the lung for carbon monoxide; FVC = forced vital capacity; IPF = idiopathic pulmonary fibrosis; ILD = interstitial lung disease; N/A = not applicable; NS = not significant; NSIP = non-specific interstitial pneumonia; SSc = systemic sclerosis; UIP = usual interstitial pneumonia.

ISSN: 1755-1536